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Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
11 papers
Recent·Most cited
V. Girik, L. Van Ek, I. Dentand Quadri, M. Azam, M. Cruz Cobo, M. Mandavit, I. Riezman, H. Riezman, A.-C. Gavin, P. Nunes-Hasler
This study develops genetically encoded fluorescent probes based on KSR1's ceramide-binding domain to track ceramide dynamics during phagocytosis and identifies distinct behaviors of different probe variants.
bioRxiv · Sep 27, 2023 · PreprintCell Biology
C. Czernecki, S. Dixit, I. Riezman, S. Innocenti, F. Pfrieger, H. Riezman, P. Scheiffele
The paper develops genetically-encoded sensors to assess cell type-specific cholesterol distribution in mouse models of neurodevelopmental disorders and identifies distinct cholesterol homeostasis phenotypes in Npc1 and Ptchd1 knock-out mice.
bioRxiv · Nov 16, 2022 · PreprintNeuroscience
C. Simon, A. Asaro, S. Feng, H. Riezman
The paper uses photoactivation and dual-isotope labeling to study phosphatidylethanolamine metabolism in living cells, revealing subcellular contributions to phospholipid remodeling.
bioRxiv · Nov 3, 2022Cell Biology
N. Jimenez-Rojo, S. Feng, J. Morstein, S. D. Pritzl, T. Harayama, A. Asaro, N. A. Veprek, C. J. Arp, M. Reynders, A. J. E. Novak, E. Kanshin, B. Ueberheide, T. Lohmuller, H. Riezman, D. Trauner
This paper introduces an optical method to control membrane fluidity using a synthetic fatty acid with an azobenzene photoswitch, demonstrating its impact on protein secretion from the ER.
bioRxiv · Feb 14, 2022 · PreprintCell Biology
L. Enkler, M. V. Pennauer, V. Szentgyörgyi, C. Prescianotto-Baschong, I. Riezman, A. Wiesyk, R. Kucharczyk, M. Spiess, H. Riezman, A. Spang
This study shows that Arf1 regulates fatty acid metabolism, affecting mitochondrial homeostasis and ATP synthesis in yeast.
bioRxiv · Jan 26, 2022 · PreprintCell Biology
B. G. Monasterio, N. Jimenez-Rojo, A. B. Garcia-Arribas, H. Riezman, F. M. Goni, A. Alonso
This study examines how sphingolipid restriction affects LY-B cell membrane properties, showing reduced membrane rigidity and altered lipid composition.
The FASEB Journal · Jun 1, 2021Peer-reviewedBiophysics
V. Girik, S. Feng, H. Hariri, W. M. Henne, H. Riezman
The paper develops a method to release lipids from the vacuole in yeast to study lipid metabolism and transport, showing Mdm1 facilitates sphingoid base to ceramide conversion and cholesterol can restore cell proliferation under sterol deprivation.
bioRxiv · May 4, 2021Cell Biology
M. Umebayashi, S. Takemoto, L. Reymond, M. Sundukova, R. Hovius, A. Bucci, P. A. Heppenstall, H. Yokota, K. Johnsson, H. Riezman
This paper develops a method to monitor the local membrane environment around the insulin receptor in living cells and finds it is dynamic, heterogeneous, and changes with receptor activation.
bioRxiv · Dec 23, 2020Cell Biology
N. Jimenez, M. Leonetti, V. Zoni, A. Colom, S. Feng, N. R. Iyengar, S. Matile, A. Roux, S. Vanni, J. S. Weissman, H. Riezman
The paper identifies hypersensitive mutants in lipid biosynthesis and trafficking genes in sphingolipid-depleted cells and shows coordinate regulation of ether and sphingolipids.
bioRxiv · Dec 19, 2019Biochemistry
C. E. Cadena Del Castillo, J. T. Hannich, A. Kaech, H. Chiyoda, M. Fukuyama, N. J. Færgeman, H. Riezman, A. Spang
This study identifies PTC-3 as a cholesterol transporter in C. elegans, showing that its loss causes cholesterol accumulation, ER defects, and lipid metabolism issues, which are rescued by reducing dietary cholesterol.
bioRxiv · Oct 23, 2019Cell Biology
A. G. Haribowo, J. T. Hannich, A. H. Michel, M. Megyeri, M. Schuldiner, B. Kornmann, H. Riezman
This study identifies cytotoxic effects of 1-deoxysphingolipid species and reveals mechanisms linking their accumulation to HSAN IA/C pathology through genetic screens and lipidomics.
bioRxiv · Jun 3, 2019Cell Biology