Author

S. Dixit

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Immunology· 2 Bioengineering· 1 Evolutionary Biology· 1 Neuroscience· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Organism:Arabidopsis· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:mouse· 2

Frequent Co-Authors

M. R. Holbrook· 2 shared A. Cooper· 1 shared A. Gomez-Cadenas· 1 shared A. Grover· 1 shared A. Mukhopadhyay· 1 shared A. Pegu· 1 shared B. Kav· 1 shared C. Czernecki· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersImmunology

M. R. Holbrook

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Author profile →

8 papers

Recent·Most cited

Evaluating polarizable biomembrane simulations against experiments

B. Kav, H. S. Antila, S. Dixit, M. S. Miettinen, J. J. Madsen, O. H. S. Ollila

This study evaluates polarizable lipid force fields against experimental data and finds non-polarizable models often perform better despite higher computational cost.

bioRxiv · Dec 1, 2023Biophysics

Governing principles of transcriptional logic out of equilibrium

S. Dixit, T. C. Middelkoop, S. Choubey

This study investigates transcriptional logic out of equilibrium and finds that non-equilibrium binding of transcription factors enables new logic operations not accessible in equilibrium.

bioRxiv · Nov 20, 2023Biophysics

Automated Protein Affinity Optimization using a 1D-CNN Deep Learning Model

J. L. McWhirter, A. Mukhopadhyay, P. Farber, G. Lakatos, S. Dixit

This paper introduces ZymeSwapNet, a 1D-CNN model for protein sequence prediction that optimizes design objectives like stability and binding specificity in antibody domains.

bioRxiv · Apr 12, 2023 · PreprintBioengineering

Cell type-specific assessment of cholesterol distribution in models of neurodevelopmental disorders

C. Czernecki, S. Dixit, I. Riezman, S. Innocenti, F. Pfrieger, H. Riezman, P. Scheiffele

The paper develops genetically-encoded sensors to assess cell type-specific cholesterol distribution in mouse models of neurodevelopmental disorders and identifies distinct cholesterol homeostasis phenotypes in Npc1 and Ptchd1 knock-out mice.

bioRxiv · Nov 16, 2022 · PreprintNeuroscience

ABA-induced SA accumulation causes higher susceptibility in B. juncea as compared to tolerant genotypes against A. brassicae

S. Dixit, A. Grover, S. Pushkar, S. Singh

This study compares the response of three Brassica species to A. brassicae infection and exogenous phytohormones, finding that B. juncea is more susceptible due to SA-ABA synergy, while tolerant genotypes show JA-mediated resistance.

bioRxiv · Apr 28, 2022 · PreprintPlant Biology

Broadly neutralizing antibodies target the coronavirus fusion peptide

C. Dacon, C. Tucker, L. Peng, C.-C. D. Lee, T.-H. Lin, M. Yuan, Y. Cong, L. Wang, L. Purser, J. K. Williams, C.-W. Pyo, I. Kosik, Z. Hu, M. Zhao, D. Mohan, , J. Tan

The paper identifies six monoclonal antibodies that broadly neutralize coronaviruses by targeting the conserved fusion peptide.

bioRxiv · Apr 11, 2022Immunology

Scalable, Micro-Neutralization Assay for Qualitative Assessment of SARS-CoV-2 (COVID 19) Virus-Neutralizing Antibodies in Human Clinical Samples

M. R. Holbrook, R. S. Bennett, E. N. Postnikova, J. Liang, R. Gross, D. Gerhardt, S. Georgia-Clark, Y. Cai, S. Yu, L. Marron, G. Kocher, S. Mazur, S. Dixit, V. V. Lukin

The paper describes a modified fluorescence reduction neutralization assay for quantitatively assessing SARS-CoV-2 neutralizing antibodies in clinical samples, demonstrating its efficiency and accuracy.

bioRxiv · Mar 5, 2021Immunology

Rapid specialization of counter defenses enables two-spotted spider mite to adapt to novel plant hosts

G. Salehipourshirazi, K. Bruinsma, H. Ratlamwala, S. Dixit, V. Arbona, E. Widemann, M. Milojevic, P. Jin, N. Bensoussan, A. Gomez-Cadenas, V. Zhurov, M. Grbic, V. Grbic

This study shows that two-spotted spider mites can rapidly evolve detoxification mechanisms to adapt to novel plant hosts within 25 generations.

bioRxiv · Feb 26, 2020Evolutionary Biology