Author

J. Morstein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biochemistry· 1 Bioengineering· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

D. Trauner· 3 shared A. Asaro· 1 shared A. Bhat· 1 shared A. J. E. Novak· 1 shared A. L. Arthur· 1 shared A. M. Bryan· 1 shared A. M. Farnoud· 1 shared A. Singh· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersBioengineering

D. Trauner

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Selective activation of intracellular β1AR using a spatially restricted antagonist

F. Liccardo, J. Morstein, T.-Y. Lin, J. Pampel, K. Shokat, R. Irannejad

This paper develops spatially restricted antagonists to selectively inhibit β1AR signaling at the plasma membrane versus intracellular compartments, revealing compartment-specific effects on downstream signaling.

bioRxiv · Nov 22, 2023 · PreprintCell Biology

Optical Control of Translation with a Puromycin-Photoswitch

T. Ko, M. Martins, J. M. Alapin, J. Morstein, E. Klann, D. H. Trauner

This paper introduces puroswitch, a photoswitchable puromycin analog that optically controls translation and enables tracking of new protein synthesis.

bioRxiv · Jul 12, 2022Biochemistry

Optical Control Of Neuronal Activities With Photoswitchable Nanovesicles

H. Xiong, K. A. Alberto, J. Youn, J. Taura, J. Morstein, X. Li, Y. Wang, D. Trauner, P. A. Slesinger, S. O. Nielsen, Z. Qin

This paper develops photoswitchable nanovesicles (azosomes) for precise optical control of molecular release in neurons, demonstrating their ability to activate dopamine receptors in cultured striatal neurons.

bioRxiv · Jun 10, 2022Bioengineering

Optical Control of Membrane Fluidity Modulates Protein Secretion

N. Jimenez-Rojo, S. Feng, J. Morstein, S. D. Pritzl, T. Harayama, A. Asaro, N. A. Veprek, C. J. Arp, M. Reynders, A. J. E. Novak, E. Kanshin, B. Ueberheide, T. Lohmuller, H. Riezman, D. Trauner

This paper introduces an optical method to control membrane fluidity using a synthetic fatty acid with an azobenzene photoswitch, demonstrating its impact on protein secretion from the ER.

bioRxiv · Feb 14, 2022 · PreprintCell Biology

Cholesterol and sphingomyelin are critical for Fcγ receptor-mediated phagocytosis of Cryptococcus neoformans by macrophages

A. M. Bryan, J. K. You, G. Li, J. Kim, A. Singh, J. Morstein, D. Trauner, N. Pereira de Sa, T. G. Normile, A. M. Farnoud, E. London, M. Del Poeta

This study shows that cholesterol and sphingomyelin in lipid rafts are essential for Fcγ receptor-mediated phagocytosis of Cryptococcus neoformans by macrophages.

bioRxiv · Nov 2, 2021Microbiology

Evolutionarily related small viral fusogens hijack distinct but modular actin nucleation pathways to drive cell-cell fusion

K. M. C. Chan, A. L. Arthur, J. Morstein, M. Jin, A. Bhat, D. Schlesinger, S. Son, D. A. Stevens, D. G. Drubin, D. A. Fletcher

This study shows that two FAST proteins use distinct actin nucleation pathways to drive cell-cell fusion, but their cytoplasmic tails are modular and functionally interchangeable.

bioRxiv · Jun 3, 2020Cell Biology