Author

H. Schneider

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Ecology· 2 Plant Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:ecology & biodiversity· 2 Organism:human· 2 Organism:plant (other)· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

C. Schroeter· 2 shared D. Schwarz· 2 shared M. Rieker· 2 shared N. Rasche· 2 shared A. Evers· 1 shared A. Heymans· 1 shared A. Perraki· 1 shared A. Wegener· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersBiochemistry

C. Schroeter

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Welding PROxAb Shuttles: A modular approach for generating bispecific antibodies via site-specific protein-protein conjugation

T. Lehmann, H. Schneider, J. Tonillo, J. Schanz, D. Schwarz, C. Schroeter, H. Kolmar, S. Hecht, J. Anderl, N. Rasche, M. Rieker, S. Dickgiesser

The paper describes a modular method to generate PROxAb Shuttles by conjugating PROTAC-binding VHHs to antibodies, enabling targeted protein degradation and bispecific antibody creation.

bioRxiv · Mar 15, 2024Biochemistry

Evidence that variation in root anatomy contributes to local adaptation in Mexican native maize

C. McLaughlin, M. Li, M. Perryman, A. Heymans, H. Schneider, J. Lasky, R. Sawers

The paper uses machine learning to link root anatomical traits with environmental variation in Mexican maize, finding trait combinations that favor reduced axial conductance in cooler, drier highland areas.

bioRxiv · Nov 14, 2023Plant Biology

PROxAb Shuttle: A non-covalent plug-and-play platform for the rapid generation of tumor-targeting antibody-PROTAC conjugates

H. Schneider, S. Jaeger, D. Koenning, N. Rasche, C. Schroeter, D. Elter, A. Evers, M. Lecomte, F. Riccardi Sirtori, D. Schwarz, A. Wegener, I. Hartung, M. Rieker

This paper introduces a platform for creating tumor-targeting antibody-PROTAC conjugates that enhances bioavailability and specificity without modifying PROTACs or antibodies.

bioRxiv · Sep 29, 2023 · PreprintBiochemistry

Modelling the effects of bioclimatic characteristics and climate change on the potential distribution of a monospecific species Colophospermum mopane (Benth.) Leonard in southern Africa.

B. K. Ngarega, V. F. Masocha, H. Schneider

This study models how climate change affects the potential distribution of Colophospermum mopane in southern Africa using Maxent, finding that solar radiation, temperature range, and precipitation are key factors.

bioRxiv · Jun 3, 2021Ecology

The epoxyeicosatrienoic pathway is intact in endothelial and smooth muscle cells exposed to aldosterone excess

L. Brunnenkant, Y. Meng, J. Sun, J. Gonzalez Marques, B. Koletzko, M. Mederos y Schnitzler, T. Gudermann, T. A. Williams, F. Beuschlein, D. A. Heinrich, C. Adolf, M. Reincke, H. Schneider

This study investigates the effect of aldosterone excess on the epoxyeicosatrienoic acid (EET) pathway in endothelial and smooth muscle cells, finding no significant changes in gene expression or EET release.

bioRxiv · Feb 4, 2021 · PreprintPhysiology

Comparative analysis of early divergent land plants and construction of DNA tools for hyper-expression in Marchantia chloroplasts

E. Frangedakis, F. Guzman-Chavez, M. Rebmann, K. Markel, Y. Yu, A. Perraki, S. W. Tse, Y. Liu, J. Rever, S. Sauret-Gueto, B. Goffinet, H. Schneider, J. Haseloff

The paper maps chloroplast transcription patterns in Marchantia and identifies DNA tools for hyper-expression in chloroplasts by testing candidate binding sites for mRNA stabilization.

bioRxiv · Nov 27, 2020 · PreprintPlant Biology

Ipomoeassin-F inhibits the in vitro biogenesis of the SARS-CoV-2 spike protein and its host cell membrane receptor

S. O'Keefe, P. Roboti, K. B. Duah, G. Zong, H. Schneider, W. Q. Shi, S. High

This study shows that ipomoeassin F inhibits the ER membrane translocation of SARS-CoV-2 spike, ORF8, and ACE2 proteins in vitro.

bioRxiv · Nov 24, 2020Biochemistry

Neither global nor consistent: a technical comment on the tree diversity-productivity analysis of Liang et al. (2016)

C. F. Dormann, H. Schneider, J. Gorges

The paper re-analyzes Liang et al. (2016) data, finding no local-scale effect of tree species richness on productivity and highlighting regional variability.

bioRxiv · Jan 20, 2019 · PreprintEcology