Author

H. T. Hu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

K. Hanawa-Suetsugu· 2 shared S. Suetsugu· 2 shared T. Nishimura· 2 shared A. Mukherjee· 1 shared A. Nain· 1 shared B. Behkam· 1 shared C. Takahashi· 1 shared D. Matsubara· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

K. Hanawa-Suetsugu

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintMay 20, 2022

Actin filaments couple the protrusive tips to the nucleus through the I-BAR domain protein IRSp53 for migration of elongated cells on 1D fibers

A. Mukherjee, J. Ron, H. T. Hu…·A. Nain

This study shows that IRSp53 couples actin filaments to the nucleus via membrane curvature during 3D cell migration on 1D fibers, affecting protrusion and contractility.

DOI 10.1101/2022.05.20.492840

experimental assaycell signaling & trafficking

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Cell BiologybioRxivPreprintApr 20, 2020

Involvement of I-BAR protein IRSp53 in tumor cell growth via extracellular microvesicle secretion

H. T. Hu, N. Sasakura, D. Matsubara…·S. Suetsugu

This study shows IRSp53 promotes tumor cell proliferation through microvesicle secretion, as evidenced by reduced secretion and phosphorylation in knockout cells and increased survival in IRSp53-deficient mice.

DOI 10.1101/2020.04.20.050492

humanmouse

𝕏 PostBluesky