Tumor Stroma Content Regulates Penetration and Efficacy of Tumor-targeting Bacteria
Y. Zhan, B. Burkel, E. J. Leaman, S. M. Ponik, B. Behkam
This study shows that high collagen content in tumors limits bacterial penetration and reduces the efficacy of Salmonella-based cancer therapy.
bioRxiv · Mar 29, 2024 · PreprintBiophysics