I. G. Macara

This study identifies a junction-dependent mechanism for mammary cell intercalation driving ductal elongation through ZO-1 dynamics and cytoskeletal rearrangements.

This study shows that apoptotic signals drive stem cell conversion to the cardiac lineage through nucleotide-mediated paracrine signaling during mesoderm specification.

The paper identifies non-canonical NF-κB signaling as a regulator of density-dependent proliferation through a CRISPR screen in murine mammary epithelial cells.

The paper shows DNA damage induces hyperplasia and lineage infidelity in epithelial tissues through non-autonomous stromal signaling, promoting stemness and tissue disorganization.

This study investigates exocyst dynamics in mammalian cells, revealing tetrameric subcomplexes that dynamically associate with vesicles and plasma membrane.