Author

I. Georgiev

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 2 Organism:rat· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

J. E. Crowe· 2 shared R. H. Carnahan· 2 shared A. A. Murji· 1 shared A. Bauer· 1 shared A. Shiakolas· 1 shared A. Trivette· 1 shared B. Doranz· 1 shared B. F. Keele· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersImmunology

J. E. Crowe

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Adaptation of a transmitted/founder simian-human immunodeficiency virus for enhanced replication in rhesus macaques

A. Bauer, E. Lindemuth, J. Joy, F. E. Marino, S. S. Docken, R. Krause, S. Mallick, K. McCormick, C. Holt, I. Georgiev, B. K. Felber, B. F. Keele, R. Veazey, M. P. Davenport, H. Li, , K. J. Bar

This paper adapts a transmitted/founder SHIV to enhance replication in rhesus macaques while preserving HIV-1 Env biology, resulting in a more fit virus for NHP HIV studies.

bioRxiv · Dec 12, 2022Microbiology

An antibody targeting the N-terminal domain of SARS-CoV-2 disrupts the spike trimer

N. Suryadevara, A. Shiakolas, L. VanBlargan, E. Binshtein, R. Chen, J. B. Case, K. Kramer, E. Armstrong, L. Myers, A. Trivette, C. Gainza, R. Nargi, C. Selverian, E. Davidson, B. Doranz, , J. E. Crowe

The paper identifies a rare antibody that targets the SARS-CoV-2 spike trimer interface, disrupting viral entry and providing protection in mice.

bioRxiv · Jan 12, 2022Immunology

Neutralization Fingerprinting Technology for Characterizing Polyclonal Antibody Responses to Dengue Vaccines

N. Raju, X. Zhan, S. Das, L. Karwal, H. Dean, J. E. Crowe, R. H. Carnahan, I. Georgiev

This study presents a computational framework to analyze neutralizing antibody specificities in response to dengue vaccines, revealing differences in immune responses based on prior infection status.

bioRxiv · Dec 2, 2021Immunology

Elicitation of neutralizing antibody responses to HIV-1 immunization with nanoparticle vaccine platforms

A. A. Murji, J. S. Qin, T. Hermanus, L. Morris, I. Georgiev

This study evaluates two nanoparticle vaccine strategies to elicit broadly neutralizing antibodies against HIV-1 by incorporating Env diversity from clade A and C strains, showing neutralization in mice and guinea pigs.

bioRxiv · Jun 3, 2021Immunology