A. Bauer

Spatiotemporally distinct responses to mechanical forces shape the developing seed of Arabidopsis

This study shows that Arabidopsis seeds undergo anisotropic and isotropic growth phases driven by distinct mechanical responses in different layers of the seed coat.

Fiber alignment in 3D collagen networks as a biophysical marker for cell contractility

This study uses fiber alignment and density in 3D collagen networks as a proxy for cell traction forces, validated in hepatic stellate cells and glioblastoma cell lines, and provides an open-source tool for drug screening.

Time-course of antipredator behavioral changes induced by the helminth Pomphorhynchus laevis in its intermediate host Gammarus pulex: the switch in manipulation according to parasite developmental stage differs between behaviors

This study examines how the helminth Pomphorhynchus laevis manipulates antipredator behaviors in its intermediate host Gammarus pulex, showing a switch in refuge use behavior but not activity rate during parasite development.

Prdm16 mutation determines sex-specific cardiac metabolism and identifies two novel cardiac metabolic regulators

This study investigates monoallelic Prdm16 mutation in mice, revealing sex-specific cardiac metabolic dysregulation and identifying Pyroxd2 and Pbxip1 as novel metabolic regulators.

Adaptation of a transmitted/founder simian-human immunodeficiency virus for enhanced replication in rhesus macaques

This paper adapts a transmitted/founder SHIV to enhance replication in rhesus macaques while preserving HIV-1 Env biology, resulting in a more fit virus for NHP HIV studies.

Dynamic traction force measurements of migrating immune cells in 3D matrices

This study measures dynamic traction forces of migrating NK cells in 3D matrices and finds that force bursts increase with matrix stiffness to aid migration through constrictions.

Viscoelastic properties of suspended cells measured with shear flow deformation cytometry

This paper introduces a microfluidic method to measure viscoelastic properties of suspended cells using shear flow deformation cytometry and demonstrates cell cycle-dependent rheological behavior.

Identification, Characterization and Synthesis of Natural Parasitic Cysteine Protease Inhibitors -- More Potent Falcitidin Analogs

The paper identifies and synthesizes natural falcitidin analogs with enhanced inhibitory activity against parasitic cysteine proteases.

Genomic and chemical decryption of the Bacteroidetes phylum for its potential to biosynthesize natural products

The paper analyzes Bacteroidetes genomes to identify natural product biosynthesis potential, discovers new antibiotics from Chitinophaga strains, and highlights taxonomical hotspots for specialized metabolites.

pyTFM: A tool for Traction Force and Monolayer Stress Microscopy

pyTFM is a tool for Traction Force and Monolayer Stress Microscopy that enables non-expert users to analyze cell-matrix tractions and stresses using synthetic and experimental data.

CropSurveyor: a scalable open-source experiment management system for distributed plant phenotyping and IoT-based crop management

CropSurveyor manages and integrates IoT-based crop phenotyping data from distributed sensors, enabling real-time monitoring and historical comparison of crop growth and environmental conditions.