Author

I. Koo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

A. D. Patterson· 2 shared A. Annalora· 1 shared A. Parolia· 1 shared B. Chen· 1 shared B. S. Halligan· 1 shared C. A. Lyssiotis· 1 shared C. Marcus· 1 shared D. A. Hanna· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

A. D. Patterson

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III

B. Chen, D. C. Stark, P. V. Jadhav, T. M. Lynn-Nguyen, B. S. Halligan, N. J. Rossiter, N. Sindoni, M. Shin, J. A. Paulo, M. Chang, I. Koo, S. Koshkin, S. Eyunni, P. Ronchi, M. T. Paulsen, , Y. M. Shah

The paper identifies fedratinib as a drug that increases endoplasmic reticulum-mitochondria contact sites by inhibiting BRD4, revealing a novel epigenetic pathway linking ERMCS to cellular metabolism.

bioRxiv · Feb 2, 2024 · PreprintCell Biology

Complex chemical signals dictate Ah receptor activation through the gut-lung axis

F. Dong, I. A. Murray, A. Annalora, D. Coslo, D. Desai, K. Gowda, J. Yang, D. Wang, I. Koo, F. Hao, S. G. Amin, A. D. Patterson, C. Marcus, G. H. Perdew

The paper shows that urolithin A enhances AHR activity in gut and lung tissues by reducing clearance via CYP1A1/1B1, suggesting a role for dietary substrates in modulating AHR signaling through the gut-lung axis.

bioRxiv · Feb 22, 2023Biochemistry