E. Hill

Syntaxin 6 delays prion protein fibril formation and prolongs presence of toxic aggregation intermediates

This study shows syntaxin-6 inhibits PrP fibril formation but prolongs toxic intermediate aggregates, suggesting it acts as an anti-chaperone in prion disease.

ct2vl: Converting Ct Values to Viral Loads for SARS-CoV-2 RT-qPCR Test Results

The paper introduces ct2vl, a Python package that converts RT-qPCR Ct values to viral loads for SARS-CoV-2 tests, enabling quantitative analysis of test results.

A Novel Propidium Monoazide-Based PCR Assay Can Measure Viable Uropathogenic E. coli in Vitro and in Vivo

This paper develops a PMA-based PCR assay to detect viable uropathogenic E. coli in urine, showing it can identify live bacteria even after antibiotic treatment.

Selective activation of Gαob by an adenosine A1 receptor agonist elicits analgesia without cardiorespiratory depression

The paper identifies BnOCPA as an A1R agonist that selectively activates Gαob, providing analgesia without cardiorespiratory depression.