Author

J. A. Dudakov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

K. Cooper· 3 shared D. Granadier· 2 shared L. Iovino· 2 shared S. Kinsella· 2 shared A. E. Flores· 1 shared A. Gagnon· 1 shared A. I. Kousa· 1 shared A. L. Gomes· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersImmunology

K. Cooper

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Author profile →

4 papers

Recent·Most cited

Age-related epithelial defects limit thymic function and regeneration

A. I. Kousa, L. Jahn, K. Zhao, A. E. Flores, D. Granadier, K. Cooper, J. M. Sheridan, A. Lemarquis, L. Sikkema, K. V. Argyropoulos, J. Tsai, A. Lazrak, K. Nichols, N. Lee, R. Ghale, , M. R. van den Brink

The paper identifies age-related thymic epithelial cell states that impair thymic regeneration and immune function through spatial and single-cell transcriptomics.

bioRxiv · Dec 16, 2021Immunology

Early age-related atrophy of cutaneous lymph nodes precipitates an early functional decline in skin immunity in mice with aging

S. A. Sonar, J. L. Uhrlaub, C. P. Coplen, G. D. Sempowski, J. A. Dudakov, M. R. M. van den Brink, B. J. LaFleur, M. Jergovic, J. Nikolich-Zugich

This study shows that skin-draining lymph nodes atrophy early in mice, leading to impaired immune function and reduced effector cell production in older age.

bioRxiv · Nov 22, 2021Immunology

Activation of the Zinc-sensing receptor GPR39 promotes T cell reconstitution after hematopoietic stem cell transplant

L. Iovino, K. Cooper, P. deRoos, S. Kinsella, C. Evandy, T. Ugrai, F. Mazziotta, K. S. Ensbey, D. Granadier, K. Hopwo, C. Smith, A. Gagnon, S. Galimberti, M. Petrini, G. R. Hill, J. A. Dudakov

bioRxiv · Sep 2, 2021 · PreprintImmunology

Attenuation of homeostatic signaling from apoptotic thymocytes triggers a global regenerative response in the thymus

S. Kinsella, C. A. Evandy, K. Cooper, L. Iovino, P. C. deRoos, K. S. Hopwo, D. W. Granadier, C. W. Smith, S. Rafii, J. A. Dudakov

This study identifies a pathway involving NOD2 and miR29c that, when attenuated, triggers regenerative responses in the thymus after acute damage, enhancing T cell recovery.

bioRxiv · Aug 31, 2020 · PreprintImmunology