Author

J. A. Hoyland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

M. Dudek· 3 shared Q.-J. Meng· 3 shared C. Lawless· 2 shared K. E. Kadler· 2 shared C. Angelucci· 1 shared C. F. Goncalves· 1 shared D. Chan· 1 shared D. Pathiranage· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersPhysiology

M. Dudek

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3 papers

Recent·Most cited

PhysiologybioRxivFeb 12, 2023

The clock transcription factor BMAL1 is a key regulator of extracellular matrix homeostasis and cell fate in the intervertebral disc

M. Dudek, H. Morris, N. Rogers…·Q.-J. Meng

This study shows that BMAL1, a circadian clock factor, regulates ECM homeostasis and cell fate in the intervertebral disc, with its loss causing ECM dysregulation and osteogenic differentiation.

DOI 10.1016/j.matbio.2023.07.002

mousebulk RNA-seq

𝕏 PostBluesky

PhysiologybioRxivOct 1, 2021

Mechanical loading and hyperosmolarity as a daily resetting cue for skeletal circadian clocks

M. Dudek, D. Pathiranage, C. F. Goncalves…·Q.-J. Meng

The paper shows mechanical loading and hyperosmolarity reset circadian clocks in skeletal tissues via the mTORC2-AKT-GSK3β pathway, inducing rhythmic gene expression.

DOI 10.1038/s41467-023-42056-1

mouseexperimental assay

𝕏 PostBluesky

PhysiologybioRxivMay 31, 2019

Circadian time series proteomics reveals daily dynamics in cartilage physiology

M. Dudek, C. Angelucci, J. P. Ruckshanthi…·Q.-J. Meng

This study uses circadian time-series proteomics to identify daily protein abundance changes in mouse articular cartilage, revealing rhythmic proteins and their dysregulation in osteoarthritis and aging.

DOI 10.1016/j.joca.2021.02.008

mouseproteomics

𝕏 PostBluesky