J. Ackermann

Macrophages foster adaptive anti-tumor immunity by ZEB1-dependent cytotoxic T cell chemoattraction

This study identifies ZEB1 as a key regulator of TAM-mediated T cell trafficking, enhancing CTL recruitment and immunosurveillance in tumors and metastases.

How cancer-associated fibroblasts promote T-cell exclusion in human lung tumors: a physical perspective

The paper models how cancer-associated fibroblasts in lung tumors create barriers that exclude T-cells, affecting tumor growth and immune response outcomes.

Aging and freezing of active nematic dynamics of cancer-associated fibroblasts by fibronectin matrix remodeling

This study investigates how fibronectin matrix remodeling by cancer-associated fibroblasts (CAFs) influences their nematic dynamics, revealing aging and freezing of defect motion in the ECM.

Onsager's variational principle in proliferating biological tissues, in presenceof activity and anisotropy

This paper applies Onsager's variational principle to model proliferating biological tissues, considering activity and anisotropy, and derives coupled partial differential equations for growth and chemical interactions.

Smart Slides for Optical Monitoring of Cellular Processes

The paper develops Smart Slides, a nanosensor-coated platform for optically monitoring dopamine release from neuronal cells in response to psychotropic substances.

Modeling the mechanics of growing epithelia with a bilayer plate theory

This paper develops a bilayer plate theory to model epithelial mechanics, showing how localized stiffness or thickness changes affect 3D shape during growth in Drosophila tissues.

Identification of Leucinostatins from Ophiocordyceps sp. as Antiparasitic Agents Against Trypanosoma cruzi

This study identifies leucinostatins from fungi as potent antiparasitic agents against Trypanosoma cruzi, with one showing in vivo efficacy in a mouse model.