K. Fuchs

Uterus and cervix anatomical changes and cervix stiffness evolution throughout pregnancy

This study quantifies uterine and cervical structural and biomechanical changes across pregnancy using ultrasound and aspiration measurements in 47 low-risk pregnancies.

Macrophages foster adaptive anti-tumor immunity by ZEB1-dependent cytotoxic T cell chemoattraction

This study identifies ZEB1 as a key regulator of TAM-mediated T cell trafficking, enhancing CTL recruitment and immunosurveillance in tumors and metastases.

Life and death in Trypillia times: Interdisciplinary analyses of the exceptional human remains from the settlement of Kosenivka, Ukraine (3700-3600 BCE)

This paper presents an interdisciplinary analysis of human remains from a Trypillia settlement, revealing insights into diet, conflict, and burial practices during the Chalcolithic period.

ZEB1-dependent modulation of fibroblast polarization governs inflammation and immune checkpoint blockade sensitivity in colorectal cancer

This study shows that ZEB1 in cancer-associated fibroblasts suppresses anti-tumor immunity and promotes metastasis, and its loss increases immune checkpoint sensitivity.

Chitin oligomers directly promote lymphoid innate and adaptive immune cell activation

This study shows chitin oligomers activate lymphoid innate and adaptive immune cells, including NK cells, B cells, and dendritic cells, through TLR2, expanding their role beyond myeloid cells.

An increase in surface hydrophobicity mediates chaperone activity in N-chlorinated proteins

This study identifies specific chlorinated residues in RidA that are critical for its chaperone activity under oxidative stress.

Neolithic genomes reveal a distinct ancient HLA allele pool and population transformation in Europe

The paper analyzes Neolithic genomes from Germany to show genetic heterogeneity and a high hunter-gatherer ancestry component in a WBC population, with distinct HLA allele pools related to viral immunity.