Author

J. B. Reichelt

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Pharmacology & Toxicology· 1

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Organism:Drosophila· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

A. Elkasaby· 1 shared A. Kasture· 1 shared C. Pifl· 1 shared D. Boytsov· 1 shared M. Freissmuth· 1 shared S. Bhat· 1 shared S. Sucic· 1 shared T. Hummel· 1 shared

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2022-2022 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Elkasaby

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivAug 11, 2022

A mechanism of uncompetitive inhibition of the serotonin transporter

S. Bhat, A. Elkasaby, A. Kasture…·W. Sandtner

This paper identifies ECSI#6 as an uncompetitive inhibitor of the serotonin transporter, showing it preferentially binds to the K+-bound inward-facing conformation and acts as a pharmacochaperone for misfolded variants.

DOI 10.7554/elife.82641

humanDrosophila

𝕏 PostBluesky