J. Conner

BET inhibitors as a therapeutic intervention in gastrointestinal gene signature-positive castration-resistant prostate cancer.

This study identifies BET inhibitors as effective against GI transcriptome-positive CRPC by targeting HNF1A and HNF4G, improving outcomes in preclinical models.

Development of a major histocompatibility complex class II conditional knockout mouse to study cell-specific and time-dependent adaptive immune responses in peripheral nerves.

This paper develops a conditional MHC class II knockout mouse to study cell-specific and time-dependent adaptive immune responses in peripheral nerves, showing resistance to autoimmune neuropathy despite MHC class II expression.

A Novel Ex Vivo Peritoneal Model to Investigate Mechanisms of Peritoneal Metastasis in Gastric Adenocarcinoma

This paper develops an ex vivo human peritoneal explant model to study gastric adenocarcinoma metastasis and shows it responds to genetic manipulations affecting implantation.

Are we ready to track climate-driven shifts in marine species across international boundaries? - A global survey of scientific bottom trawl data

This study evaluates global scientific bottom trawl data to assess challenges in tracking climate-driven marine species redistributions and proposes a framework for improved data sharing and management.