J. Enderlein

Conformational dynamics of electrostatically charged Intrinsically Disordered Proteins

The paper studies the conformational dynamics of highly charged intrinsically disordered proteins using a computational model and experimental measurements, finding slower loop-closing rates compared to uncharged IDPs.

Variational calculus approach to Zernike polynomials with application to fluorescence correlation spectroscopy

This paper derives Zernike polynomials using variational calculus and applies them to model optical aberrations in fluorescence microscopy.

Super-resolution going viral: T4 virus particles as perfect nature-designed 3D-Bio-NanoRulers

The paper introduces bacteriophage T4 as a 3D bio-ruler for super-resolution imaging, demonstrating its structure and potential as a benchmark.

Three-dimensional multi-target super-resolution microscopy of cells using Metal-Induced Energy Transfer and DNA-PAINT

This paper introduces MIET-PAINT, a method combining DNA-PAINT and Metal-Induced Energy Transfer to achieve nanometer-scale 3D imaging with high multiplexing capability.

Nanoscale architecture and dynamics of CaV1.3 channel clusters in cardiac myocytes revealed by single channel nanoscopy

This study uses super-resolution imaging to reveal the dynamic nanoscale architecture of CaV1.3 channel clusters in cardiac myocytes, showing mobile channels within nanodomains rather than dense packing.

Observation of E-cadherin Adherens Junctions Variation with Metal-induced Energy Transfer Imaging/Spectroscopy

This study uses metal-induced energy transfer imaging to analyze E-cadherin junction dynamics and identifies a transient X-dimer state and its impact on membrane displacement.

Doubling the resolution of fluorescence-lifetime single-molecule localization microscopy with image scanning microscopy

This paper combines FL-SMLM with ISM to improve lateral localization accuracy and eliminate chromatic aberration in single-molecule imaging.

Metal-induced energy transfer (MIET) imaging of cell surface engineering with multivalent DNA nanobrushes

This paper uses MIET imaging to measure inter-membrane distances with nanometer precision using DNA nanobrushes to manipulate cell-cell interactions.

Photophysical studies at cryogenic temperature reveal a novel photoswitching mechanism of rsEGFP2

This study reveals a novel photoswitching mechanism of rsEGFP2 at cryogenic temperatures using SMLM, showing distinct dark states and light-dependent switching behavior.

Measuring sub-nanometer fluctuations at microsecond temporal resolution with metal- and graphene-induced energy transfer spectroscopy

This paper introduces a new method combining MIET/GIET with FCS to measure sub-nanometer membrane fluctuations at microsecond resolution, validated on model membranes and human red blood cells.

Metal-Induced Energy Transfer (MIET) for Live-Cell Imaging with Fluorescent Proteins

This paper demonstrates the application of MIET imaging for live-cell imaging with fluorescent proteins, achieving nanometer axial resolution with minimal phototoxicity across multiple cell types and proteins.

A DNA-based optical force sensor for live-cell applications

This paper introduces a DNA-based FRET sensor for non-invasive optical monitoring of intracellular mechanical forces in vitro and in living cells.

Isotropic Three-Dimensional Dual-Color Super-Resolution Microscopy with Metal-Induced Energy Transfer

The paper combines MIET imaging with dSTORM to achieve isotropic 3D super-resolution and dual-color imaging of sub-cellular structures.

Electrically Controlling and Optically Observing the Membrane Potential of Supported Lipid Bilayers

This paper describes a platform for supported lipid bilayers that can be electrically controlled and optically probed to study membrane polarization dynamics.

Mapping Activity-Dependent Quasi-Stationary States of Mitochondrial Membranes with Graphene-Induced Energy Transfer Imaging

The paper uses GIET imaging to map mitochondrial membrane states before and during ATP synthesis, showing a 2 nm reduction in inter-membrane space.

Instant three color multi-plane fluorescence microscopy

This paper introduces a multi-plane multi-color fluorescence microscope capable of rapid volumetric imaging of fixed and living cells.

Gradual Compaction of the Nascent Peptide During Cotranslational Folding on the Ribosome

The paper uses FPA and PET-FCS to study cotranslational folding of the HemK N-terminal domain, showing compaction starts early and structural fluctuations decrease as the domain moves away from the ribosome.

Confocal Laser-Scanning Fluorescence-Lifetime Single-Molecule Localisation Microscopy

This paper introduces FL-SMLM, a technique combining FL-CLSM and SMLM to achieve fluorescence-lifetime super-resolution imaging with single-molecule localization.

Three-dimensional beating dynamics of Chlamydomonas flagella

This study uses a multi-plane phase-contrast microscope to observe three-dimensional torsional dynamics of Chlamydomonas flagella and proposes a mechanism involving dynein motors and intrinsic twist.

Dimerization of human drebrin-like protein governs its biological activity

This study investigates the dimerization of human DBNL and its impact on biological activity through biophysical and imaging techniques.

Nanobody Detection of Standard Fluorescent Proteins Enables Multi-Target DNA-PAINT with High Resolution and Minimal Displacement Errors

This paper uses nanobodies to reduce displacement errors in DNA-PAINT, enabling high-resolution multi-target imaging with minimal displacement.

Photon yield enhancement of red fluorophores at cryogenic temperatures

This study examines how cooling fluorescent dyes to cryogenic temperatures increases photon yield and improves localization precision in single molecule microscopy.