J. Karslake

This study investigates how HP1 proteins recognize H3K9me with high specificity despite low-affinity binding, showing that oligomerization compensates for this and enables heterochromatin localization.

The paper shows that delayed antibiotic exposure can cause population collapse in E. faecalis communities with drug-resistant subpopulations, revealing density-dependent dynamics.

This study shows that maintaining large populations of drug-sensitive bacteria can delay the rise of drug-resistant bacteria using containment strategies.

SMAUG uses nonparametric Bayesian statistics to analyze single-molecule trajectories, providing mobility states, diffusion coefficients, and transition probabilities in both prokaryotic and eukaryotic systems.