Author

D. A. Williamson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 6 Evolutionary Biology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 7 Approach:experimental assay· 5 Assay:whole-genome sequencing· 4 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:host-pathogen & immune response· 3 Approach:statistical model· 3 Organism:bacteria (other)· 2 Research Focus:differential expression· 2

Frequent Co-Authors

G. Taiaroa· 5 shared T. P. Stinear· 4 shared B. P. Howden· 2 shared D. J. Ingle· 2 shared L. M. Judd· 2 shared T. Seemann· 2 shared T. Tran· 2 shared Y. H. Grad· 2 shared

Activity by Year

2018-2023 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersMicrobiology

G. Taiaroa

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

The inter-continental population dynamics of Neisseria gonorrhoeae

M. N. Osnes, O. B. Brynildsrud, K. Alfsnes, L. van Dorp, S. A. McKeand, J. Ross, K. Town, J. De Korne-Elenbaas, A. van Dam, S. Bruisten, B. F. de Blasio, D. A. Caugant, Y. H. Grad, D. A. Williamson, F. Balloux, , V. Eldholm

This study reconstructs the global population dynamics of Neisseria gonorrhoeae using phylogenomic analysis, revealing expanding effective population size and distinct transmission patterns between Norway and Victoria, Australia.

bioRxiv · Aug 2, 2023 · PreprintMicrobiology

A transmission chain linking Mycobacterium ulcerans with Aedes notoscriptus mosquitoes, possums and human Buruli ulcer cases in southeastern Australia

P. T. Mee, A. H. Buultjens, J. Oliver, K. Brown, J. C. Crowder, J. L. Porter, E. C. Hobbs, L. M. Judd, G. Taiaroa, N. Puttharak, D. A. Williamson, K. R. Blasdell, E. L. Tay, R. Feldman, M. O. Muzari, , S. E. Lynch

The paper investigates the transmission chain of Mycobacterium ulcerans between mosquitoes, possums, and humans in southeastern Australia, finding a significant association between M. ulcerans and Aedes notoscriptus mosquitoes.

bioRxiv · May 7, 2023 · PreprintMicrobiology

Rapid recall and de novo T cell responses during SARS-CoV-2 breakthrough infection

M. Koutsakos, A. Reynaldi, W. S. Lee, J. Nguyen, T. Amarasena, G. Taiaroa, P. Kinsella, K. C. Liew, T. Tran, H. E. Kent, H.-X. Tan, L. C. Rowntree, T. H. O. Nguyen, P. Thomas, K. Kedzierska, , J. A. Juno

This study examines T cell responses during SARS-CoV-2 breakthrough infections, showing rapid recall of memory T cells and a correlation between CD8+ T cell activation and viral clearance.

bioRxiv · Dec 19, 2022Immunology

Quantifying plasmid movement in drug-resistant Shigella species using phylodynamic inference

N. F. Müller, R. R. Wick, L. M. Judd, D. A. Williamson, T. Bedford, B. Howden, S. Duchene, D. J. Ingle

This paper introduces a method to quantify plasmid movement in Shigella species over time, finding higher transfer rates for small plasmids and recent dissemination of a multidrug-resistant plasmid.

bioRxiv · Oct 27, 2022Evolutionary Biology

Transcriptional and epi-transcriptional dynamics of SARS-CoV-2 during cellular infection

J. J.- Y. Chang, D. Rawlinson, M. E. Pitt, G. Taiaroa, J. Gleeson, C. Zhou, F. L. Mordant, R. De Paoli-Iseppi, L. Caly, D. F. J. Purcell, T. P. Stinear, S. L. Londrigan, M. B. Clark, D. A. Williamson, K. Subbarao, L. J. M. Coin

This study examines SARS-CoV-2 transcriptional and epi-transcriptional dynamics using long-read sequencing in human and primate infection models, revealing distinct patterns of sgRNA regulation and modification.

bioRxiv · Dec 22, 2020Microbiology

Global population structure and genotyping framework for genomic surveillance of the major dysentery pathogen, Shigella sonnei

J. Hawkey, K. Paranagama, K. S. Baker, R. J. Bengtsson, F.-X. Weill, N. R. Thomson, S. Baker, L. Cerdeira, Z. Iqbal, M. Hunt, D. J. Ingle, T. J. Dallman, C. Jenkins, D. A. Williamson, K. E. Holt

The paper develops a genomic framework and genotyping scheme for Shigella sonnei to identify resistance determinants from WGS data, revealing common genotypes linked to antimicrobial resistance and global spread.

bioRxiv · Oct 29, 2020Microbiology

Validation of a Single-step, Single-tube Reverse Transcription-Loop-Mediated Isothermal Amplification Assay for Rapid Detection of SARS-CoV-2 RNA

J. Y. Lee, N. Best, J. L. McAuley, J. Porter, T. Seemann, M. B. Schultz, M. Sait, N. Orlando, K. Mercoulia, S. A. Ballard, J. Druce, T. Tran, M. Catton, M. J. Pryor, H. L. Cui, , T. P. Stinear

The paper validates a single-step, single-tube RT-LAMP assay for rapid SARS-CoV-2 detection with high specificity and sensitivity.

Journal of Medical Microbiology · Sep 1, 2020Peer-reviewedMicrobiology

Increased antibiotic susceptibility in Neisseria gonorrhoeae through adaptation to the cervical environment

K. C. Ma, T. D. Mortimer, A. L. Hicks, N. E. Wheeler, L. Sanchez-Buso, D. Golparian, G. Taiaroa, D. H. Rubin, Y. Wang, D. A. Williamson, M. Unemo, S. R. Harris, Y. H. Grad

This study identifies loss-of-function mutations in efflux pumps as a mechanism for increased antibiotic susceptibility in Neisseria gonorrhoeae cervical isolates.

Nature Communications · Aug 17, 2020Peer-reviewedMicrobiology

Cellular and structural basis of synthesis of the unique intermediate dehydro-F420-0 in mycobacteria

R. Grinter, B. Ney, R. Brammananth, C. K. Barlow, P. R. F. Cordero, D. L. Gillett, T. Izore, M. Cryle, L. Harold, G. M. Cook, G. Taiaroa, D. A. Williamson, A. C. Warden, J. G. Oakeshott, M. C. Taylor, , C. Greening

This study resolves the biosynthesis pathway of F420 in mycobacteria by showing phosphoenolpyruvate, not 2-phospholactate, is the precursor and identifies the structural mechanism of dehydro-F420-0 production.

bioRxiv · Feb 27, 2020Biochemistry

Remodelling of pSK1 Family Plasmids and Enhanced Chlorhexidine Tolerance in Methicillin-Resistant Staphylococcus aureus

S. L. Baines, S. O. Jensen, N. Firth, A. Goncalves da Silva, T. Seemann, G. P. Carter, D. A. Williamson, B. P. Howden, T. P. Stinear

This study examines the evolution of pSK1 family plasmids in MRSA ST239 isolates over 32 years, showing their role in enhancing chlorhexidine tolerance and gentamicin resistance.

bioRxiv · Oct 31, 2018Evolutionary Biology