Author

J. M. Rini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1 Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:protein structure· 1

Frequent Co-Authors

Z. Li· 3 shared S. Mubareka· 2 shared A. J. McGeer· 1 shared A. P. Dupuis· 1 shared A.-C. Gingras· 1 shared B. A. Minassian· 1 shared B. Boon· 1 shared B. Rathod· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

Z. Li

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

MicrobiologybioRxivApr 8, 2021

Intranasal HD-Ad Vaccine Protects the Upper and Lower Respiratory Tracts of hACE2 Mice against SARS-CoV-2

H. Cao, J. Mai, Z. Zhou…·J. Liu

DOI 10.1186/s13578-021-00723-0

mouseexperimental assay

𝕏 PostBluesky

ImmunologybioRxivJul 10, 2020

A simple protein-based surrogate neutralization assay for SARS-CoV-2

K. T. Abe, Z. Li, R. Samson…·A.-C. Gingras

The paper introduces a protein-based assay to detect neutralizing antibodies against SARS-CoV-2, showing it correlates with traditional viral neutralization tests.

DOI 10.1172/jci.insight.142362

proteomicsexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivPreprintJun 5, 2020

Synthetic antibodies neutralize SARS-CoV-2 infection of mammalian cells

S. Miersch, M. Ustav, Z. Li…·S. S. Sidhu

The paper describes synthetic monoclonal antibodies that neutralize SARS-CoV-2 by binding to the spike protein and blocking ACE2 receptor interaction, showing potent antiviral activity.

DOI 10.1101/2020.06.05.137349

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivJan 22, 2020

Exploiting toxin internalization receptors to enhance delivery of proteins to lysosomes for enzyme replacement therapy

S. Sugiman-Marangos, G. L. Beilhartz, X. Zhao…·R. A. Melnyk

This study creates a chimera of diphtheria toxin and TPP1 to enhance lysosomal enzyme delivery, showing improved uptake and efficacy in a mouse model.

DOI 10.1126/sciadv.abb0385

mouseprotein structure

𝕏 PostBluesky