Author

M. Olshansky

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 4 Research Focus:chromatin & epigenetic regulation· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2

Frequent Co-Authors

S. J. Turner· 4 shared A. Barugahare· 2 shared B. E. Russ· 2 shared J. Li· 2 shared A. E. Morey· 1 shared A. Fletcher· 1 shared A. Fulcher· 1 shared A. J. Corbett· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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4 shared papersImmunology

S. J. Turner

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Targeting BMI-1 to deplete antibody-secreting cells in autoimmunity

J. Polmear, L. Hailes, M. Olshansky, M. Rischmueller, E. L'Estrange-Stranieri, A. Fletcher, M. Hibbs, V. Bryant, K. Good-Jacobson

This study shows that inhibiting BMI-1 reduces antibody-secreting cells in autoimmune models, suggesting BMI-1 as a therapeutic target for antibody-mediated autoimmune diseases.

bioRxiv · Jul 27, 2023Immunology

Active maintenance of CD8+ T cell naivety through regulation of global genome architecture

B. E. Russ, K. Tsyganov, S. Quon, B. Yu, J. Li, J. K. Lee, M. Olshansky, Z. He, P. F. Harrison, A. Barugahare, M. See, S. Nuessing, A. E. Morey, V. A. Udupa, T. J. Bennett, , S. J. Turner

This study shows that transcription factors maintain CD8+ T cell naivety by enforcing a distinct chromatin architecture that remodels upon activation.

bioRxiv · Feb 26, 2023 · PreprintImmunology

MOV10 facilitates messenger RNA decay in an N6-methyladenosine (m6A) dependent manner to maintain the mouse embryonic stem cells state

M. Mehravar, Y. Kumar, M. Olshansky, P. Dakle, M. J. Bullen, V. K. Pandey, D. Bansal, C. Dent, D. Hathiwala, Z. Zhang, H. Gandhi, A. Fulcher, C. Huang, J. Price, S. Arumugam, , P. P. Das

The paper identifies MOV10 as a new m6A-reader that facilitates mRNA decay via m6A to regulate the WNT/β-CATENIN pathway and maintain mouse embryonic stem cell state.

bioRxiv · Aug 11, 2021 · PreprintBiochemistry

Saturation of influenza virus neutralization and antibody consumption can both lead to bistable growth kinetics

S. Xu, A. W. C. Yan, H. Peck, L. Gillespie, I. G. Barr, X. Yang, S. J. Turner, C. M. Donato, T. Zhang, M. Olshansky, V. Dhanasekaran

The paper uses mathematical models and focus reduction assays to show that influenza virus neutralization and antibody consumption can lead to bistable growth kinetics, explaining reinfection and vaccine efficacy.

bioRxiv · Mar 2, 2020 · PreprintMicrobiology

KDM6B-dependent chromatin remodelling underpins effective virus-specific CD8+ T cell differentiation.

J. Li, K. Hardy, M. Olshansky, A. Barugahare, L. J. Gearing, J. E. Prier, X. Y. Sng, M. L. T. Nguyen, D. Piovesan, B. E. Russ, N. L. La Gruta, P. Hertzog, S. Rao, S. J. Turner

This study identifies KDM6B-dependent chromatin remodelling as critical for virus-specific CD8+ T cell differentiation and memory formation.

bioRxiv · Feb 3, 2020 · PreprintImmunology

Activation and in vivo evolution of the MAIT cell transcriptome in mice and humans reveals diverse functionality

T. S. C. Hinks, E. Marchi, M. Jabeen, M. Olshansky, A. Kurioka, T. J. Pediongco, B. S. Meehan, L. Kostenko, S. J. Turner, A. J. Corbett, Z. Chen, P. Klenerman, J. McCluskey

The paper defines the transcriptome of activated MAIT cells in mice and humans and shows how it changes during infection phases, revealing a tissue repair phenotype.

bioRxiv · Dec 9, 2018 · PreprintImmunology