Author

J. McColl

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:imaging· 2 Approach:microscopy & imaging analysis· 2 Research Focus:clustering· 1 Research Focus:development & morphogenesis· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

A. M. Santos· 3 shared A. Ponjavic· 3 shared D. Klenerman· 3 shared S. J. Davis· 3 shared A. R. Carr· 2 shared S. F. Lee· 2 shared A. H. Lippert· 1 shared A. Handa· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersBiophysics

A. M. Santos

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

TECPR1 provides E3-ligase like activity to the ATG5-ATG12 complex to conjugate LC3/ATG8 to damaged lysosomes

Y. Wang, M. Jefferson, J. Mccoll, P. Verkade, U. Mayer, T. Wileman

This study shows TECPR1 can substitute for ATG16L1 to conjugate LC3 to damaged lysosomes by providing E3-ligase activity to the ATG5-ATG12 complex.

bioRxiv · Jun 24, 2023 · PreprintCell Biology

resPAINT: Accelerating volumetric super-resolution localisation microscopy by active control of probe emission

E. Sanders, A. R. Carr, E. Bruggeman, M. Koerbel, S. I. Benaissa, R. Donat, A. M. Santos, J. McColl, K. O'Holleran, D. Klenerman, S. J. Davis, S. F. Lee, A. Ponjavic

The paper introduces resPAINT, a method that enhances volumetric super-resolution microscopy by actively controlling probe emission, achieving up to 50-fold faster localisation rates without sacrificing contrast.

bioRxiv · Apr 14, 2022Biophysics

Robust T-cell signaling triggered on soft polydimethylsiloxane-supported lipid-bilayers

A. H. Lippert, I. B. Dimov, A. Winkel, J. McColl, J. Humphrey, K. Y. Chen, A. M. Santos, E. Jenkins, K. Franze, S. Davis, D. Klenerman

This study investigates T-cell signaling on soft lipid bilayers, finding early calcium signaling is not mechanosensitive but phosphatase exclusion occurs on soft substrates.

bioRxiv · Jun 5, 2020 · PreprintBiophysics

vLUME: 3D Virtual Reality for Single-molecule Localization Microscopy

A. Spark, A. Kitching, D. Esteban-Ferrer, A. Handa, A. R. Carr, L.-M. Needham, A. Ponjavic, M. Da Cunha Santos, J. McColl, C. Leterrier, S. J. Davis, R. Henriques, S. F. Lee

vLUME is a VR software for visualizing 3D SMLM data, enabling segmentation and quantification of fluorescence puncta with high fidelity.

bioRxiv · Jan 20, 2020Biophysics

The costs of close contact: Visualizing the energy landscape of cell contacts at the nanoscale

A. Lippert, K. Kulenkampff, J. McColl, D. Klenerman, A. M. Santos, A. Ponjavic, S. Lee, S. J. Davis

This paper uses quantum dots to study how protein size affects diffusion and entry into cell contacts, revealing size-dependent exclusion and reduced diffusion in dense adhesion protein regions.

bioRxiv · Jul 9, 2019Biophysics