J. McGovern

Damage sensing through TLR9 Regulates Inflammatory and Antiviral Responses During Influenza Infection

This study shows that TLR9 sensing of tissue damage during influenza infection promotes inflammation and antiviral responses, but its absence leads to impaired viral clearance and prolonged lung injury.

The Effect of Adrenalectomy on Bleomycin-Induced Pulmonary Fibrosis in Mice

This study investigates the effect of adrenalectomy on bleomycin-induced pulmonary fibrosis in mice, finding that adrenalectomy reduces lung remodeling but not collagen deposition.

Aerosolized α1 adrenoreceptor antagonism does not affect experimentally induced lung fibrosis in animal models

This study tests if inhaled terazosin, an α1 adrenoreceptor antagonist, reduces lung fibrosis in animal models but finds no significant effect.

NKG2D signaling regulates IL-17A-producing γδT cells to promote cancer progression

This study shows that NKG2D signaling promotes IL-17A-producing γδT cells, which drive cancer progression in intestinal tumors.

Three-dimensional experiments and individual based simulations show that cell proliferation drives melanoma nest formation in human skin tissue

Quantifying Rates Of Cell Migration And Cell Proliferation In Co-Culture Barrier Assays Reveals How Skin And Melanoma Cells Interact During Melanoma Spreading And Invasion

The paper quantifies cell migration and proliferation rates in co-culture assays to study melanoma-skin cell interactions, finding no evidence of interactions beyond cell-to-cell contact and crowding.