Spatiotemporal single-cell profiling of gastrointestinal GVHD reveals invasive and resident memory T cell states.
V. Tkachev, J. Kaminski, E. L. Potter, S. N. Furlan, A. Yu, D. J. Hunt, C. McGuckin, H. Zheng, L. Colonna, U. Gerdemann, J. Carlson, M. Hoffman, J. Olvera, C. English, A. Baldessari, , L. S. Kean
The paper uses SIVS and scRNA-seq to analyze T cell infiltration and residency in the GI tract during aGVHD, identifying genes associated with tissue invasiveness and TRM programming.
bioRxiv · Jul 20, 2020 · PreprintImmunology