Author

J. Perrigoue

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

J. R. Friedman· 2 shared A. Das· 1 shared A. Di Narzo· 1 shared A. Kasarskis· 1 shared A. Levescot· 1 shared A. Livanos· 1 shared A. Pellagatti· 1 shared A. Stojmirovic· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

J. R. Friedman

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Author profile →

3 papers

Recent·Most cited

Ribosomal protein control of hematopoietic stem cell transformation through regulation of metabolism.

B. Harris, D. K. Singh, B. Truong, M. Rhodes, R. Price, S. Shinton, M. Verma, B. Aylward, S. P. Fahl, S. R. Sprinkle, S. Aminov, M. Wang, Y. Zhang, J. Perrigoue, R. Kessel, , D. L. Wiest

This study shows that reduced RPL22 expression in hematopoietic stem cells promotes leukemia by altering metabolism and increasing lipid synthesis via Lin28b.

bioRxiv · May 31, 2023Cancer Biology

Intestinal inflammation modulates the expression of ACE2 and TMPRSS2 and potentially overlaps with the pathogenesis of SARS-CoV-2 related disease

M. Suarez-Farinas, M. Tokuyama, G. Wei, R. Huang, A. Livanos, D. Jha, A. Levescot, H. Irizar, R. Kosoy, S. Cording, W. Wang, H. Irizar, R. Ungaro, A. Di Narzo, G. Martinez-Delgado, , S. Mehandru

The paper examines how intestinal inflammation affects ACE2 and TMPRSS2 expression and identifies shared molecular networks between COVID-19 and IBD.

bioRxiv · May 21, 2020Immunology

A negative role for the interleukin-2-inducible T-cell kinase (ITK) in human Foxp3+ Treg differentiation

P. Mamontov, R. A. Eberwine, J. Perrigoue, A. Das, J. R. Friedman, J. R. Mora

This study shows that ITK knockdown increases Foxp3+ TREG differentiation and suppressive function in human T cells, suggesting ITK as a target to enhance TREGs in autoimmune diseases.

bioRxiv · Aug 7, 2018Immunology