Author

S. Shinton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1

Frequent Co-Authors

A. Verma· 2 shared B. Aylward· 2 shared D. L. Wiest· 2 shared M. Rhodes· 2 shared A. Contreras· 1 shared A. Mihai· 1 shared A. Pellagatti· 1 shared A. V. Contreras· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersImmunology

A. Verma

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

E protein control of NKgammadeltaT cell development through both generation and function of the stereotypic Vgamma1Vdelta6.3 TCR

D. L. Wiest, A. Mihai, S.-Y. Lee, S. Shinton, M. I. Parker, A. V. Contreras, B. Zhang, M. Rhodes, R. L. Dunbrack, J. C. Zuniga-Pflucker, M. Ciofani, Y. Zhuang

This study shows that Id3 deficiency affects the development of gamma delta T cell subsets by regulating the generation and function of the Vgamma1Vdelta6.3 TCR.

bioRxiv · Jan 4, 2024 · PreprintImmunology

E-proteins set the threshold for optimal TCF1 expression during αβ T cell development.

A. Verma, B. Aylward, F. Ma, C. A. Sherman, L. Chopp, S. Shinton, R. Roy, S. Fahl, A. Contreras, B. Koenitzer, P. Awasthi, K. Mazan-Mamczarz, S. De, N. Ollikainen, X. Qiu, , J. M. Sen

This study shows E-proteins regulate TCF1 expression thresholds during T cell development, with EPE3 being critical for TCF1 levels and T cell differentiation.

bioRxiv · Nov 6, 2023 · PreprintImmunology

Ribosomal protein control of hematopoietic stem cell transformation through regulation of metabolism.

B. Harris, D. K. Singh, B. Truong, M. Rhodes, R. Price, S. Shinton, M. Verma, B. Aylward, S. P. Fahl, S. R. Sprinkle, S. Aminov, M. Wang, Y. Zhang, J. Perrigoue, R. Kessel, , D. L. Wiest

This study shows that reduced RPL22 expression in hematopoietic stem cells promotes leukemia by altering metabolism and increasing lipid synthesis via Lin28b.

bioRxiv · May 31, 2023Cancer Biology