Author

J. Rayes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

S. P. Watson· 3 shared A. Brill· 2 shared B. Grygielska· 2 shared A. Alshayea· 1 shared A. Carestia· 1 shared A. Croft· 1 shared A. F. Cunningham· 1 shared A. O. Khan· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersImmunology

S. P. Watson

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Spleen tyrosine kinase inhibition mitigates hemin-induced thromboinflammation in the lung and kidney of sickle cell mice

J. El-Awaisi, G. Perrella, N. Mayor, V. Tinkova, S. J. Cleary, B. Grygielska, S. P. Watson, J. D. Dimitrov, A. Brill, P. L. Nicolson, D. Kavanagh, N. Kalia, J. Rayes

This study shows that Syk inhibition reduces hemin-induced thromboinflammation and improves perfusion in the lungs and kidneys of sickle cell mice.

bioRxiv · May 4, 2024 · PreprintPathology

Discrete and conserved inflammatory signatures drive thrombosis in different organs after Salmonella infection

M. Perez-Toledo, N. Beristain-Covarrubias, J. Pillaye, R. R. Persaud, E. Marcial-Juarez, S. E. Jossi, J. R. Hitchcock, A. Alshayea, W. M. Channell, R. E. Lamerton, D. P. Kavanagh, A. Carestia, W. G. Horsnell, I. R. Henderson, N. Mackman, , A. F. Cunningham

This study identifies discrete inflammatory signatures driving thrombosis in the spleen and liver after Salmonella infection, revealing both organ-specific and shared mechanisms.

bioRxiv · Jan 16, 2024 · PreprintImmunology

Human bone marrow organoids for disease modelling, discovery and validation of therapeutic targets in hematological malignancies

A. O. Khan, M. Colombo, J. S. Reyat, G. Wang, A. Rodriguez-Romera, W. X. Wen, L. Murphy, B. Grygielska, C. Mahony, A. Stone, A. Croft, D. C. Bassett, G. Pooligasundarampillai, A. Roy, S. Gooding, , B. Psaila

This paper develops human bone marrow organoids to model hematological malignancies and validate therapeutic targets.

bioRxiv · Mar 14, 2022Cancer Biology

CLEC-2 promotes inflammatory peritoneal macrophage emigration to draining lymph nodes during endotoxemia

J. H. Bourne, N. Beristain Covarrubias, M. zuidscherwoude, J. Campos, Y. Di, E. Garlick, M. Colicchia, L. V. Terry, S. G. Thomas, A. Brill, J. Barry, S. P. Watson, J. Rayes

This study identifies that recombinant CLEC-2-Fc promotes the emigration of inflammatory peritoneal macrophages to draining lymph nodes, reducing local inflammation during endotoxemia.

bioRxiv · Dec 21, 2020 · PreprintImmunology