Author

D. Kavanagh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Brill· 1 shared A. Ehteda· 1 shared A. Gopalakrishnan· 1 shared A. Khan· 1 shared A. Lee· 1 shared A. W. Caulk· 1 shared B. Grygielska· 1 shared B. S. Rayner· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperPathology

A. Brill

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Chromatin remodeling with combined FACT and BET inhibition disrupts oncogenic transcription in Diffuse Midline Glioma

H. Holliday, A. Khan, A. Ehteda, H. Nguyen, S. E. Ross, N. Jayatilleke, A. Gopalakrishnan, E. Wang, Y. Colino Sanguino, D. Kavanagh, X. Guo, J. Liu, D. Lawrence, C. X. Sun, R. Lehmann, , D. S. Ziegler

This study shows that combining FACT and BET inhibition disrupts oncogenic transcription and extends survival in Diffuse Midline Glioma models.

bioRxiv · Jun 6, 2024 · PreprintCancer Biology

Spleen tyrosine kinase inhibition mitigates hemin-induced thromboinflammation in the lung and kidney of sickle cell mice

J. El-Awaisi, G. Perrella, N. Mayor, V. Tinkova, S. J. Cleary, B. Grygielska, S. P. Watson, J. D. Dimitrov, A. Brill, P. L. Nicolson, D. Kavanagh, N. Kalia, J. Rayes

This study shows that Syk inhibition reduces hemin-induced thromboinflammation and improves perfusion in the lungs and kidneys of sickle cell mice.

bioRxiv · May 4, 2024 · PreprintPathology

Paradoxical Aortic Stiffening and Subsequent Cardiac Dysfunction in Hutchinson-Gilford Progeria Syndrome

S.-I. Murtada, Y. Kawamura, A. W. Caulk, H. Ahmadzadeh, N. Mikush, K. Zimmerman, D. Kavanagh, D. Weiss, M. Latorre, Z. W. Zhuang, G. S. Shadel, D. T. Braddock, J. D. Humphrey

This study shows that aortic stiffening and cardiac dysfunction in HGPS mice occur due to loss of smooth muscle function and proteoglycan accumulation, independent of sex, with potential therapeutic implications.

bioRxiv · Oct 2, 2019Bioengineering