Author

B. Bauer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 2 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1

Frequent Co-Authors

J.-M. Peters· 3 shared C. Dekker· 2 shared I. F. Davidson· 2 shared R. Barth· 2 shared A. Beck-Sickinger· 1 shared A. C. Garcia· 1 shared A. Koch· 1 shared A. Schmidt· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersBiophysics

J.-M. Peters

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Author profile →

6 papers

Recent·Most cited

Mechanism of TAX1BP1 recruitment in aggrephagy to switch from cargo collection to sequestration

B. Bauer, J. Idinger, M. Schuschnig, L. Ferrari, S. Martens

The paper investigates how TAX1BP1 recruits the autophagy machinery to switch from cargo collection to sequestration in aggrephagy.

bioRxiv · May 17, 2024Cell Biology

Cohesin supercoils DNA during loop extrusion

I. F. Davidson, R. Barth, S. Horn, R. Janissen, K. Nagasaka, G. Wutz, R. R. Stocsits, B. Bauer, C. Dekker, J.-M. Peters

This study shows cohesin supercoils DNA during loop extrusion, influencing genome architecture through both looping and supercoiling.

bioRxiv · Mar 22, 2024Biochemistry

Somatic hypermutation patterns in immunoglobulin variable regions are established independently of the local transcriptional landscape

U. E. Schoeberl, J. Fitz, K. Froussios, R. Valieris, M. Makharova, I. Ourailidis, B. Bauer, T. Neumann, E.-M. Wiedemann, M. Steininger, A. C. Garcia, M. Mastrovito, H. Mouquet, I. Silva, R. Pavri

The paper examines SHM patterns in immunoglobulin variable regions and finds they are not significantly correlated with local transcriptional features.

bioRxiv · May 21, 2022 · PreprintImmunology

SMC complexes can traverse physical roadblocks bigger than their ring size

B. Pradhan, R. Barth, E. Kim, I. F. Davidson, B. Bauer, T. van Laar, W. Yang, J.-K. Ryu, J. van der Torre, J.-M. Peters, C. Dekker

The paper shows that SMC complexes can extrude DNA loops around large DNA-bound obstacles, suggesting a nontopological mechanism for loop extrusion.

bioRxiv · Jul 15, 2021Biophysics

Structures of active melanocortin-4 receptor--Gs-protein complexes with NDP-α-MSH and setmelanotide

N. A. Heyder, G. Kleinau, D. Speck, A. Schmidt, S. Paisdzior, M. Szczepek, B. Bauer, A. Koch, M. Gallandi, D. Kwiatkowski, J. Bürger, T. Mielke, A. Beck-Sickinger, P. W. Hildebrand, C. M. T. Spahn, , P. Scheerer

The paper presents cryo-EM structures of MC4R-Gs complexes with NDP-α-MSH and setmelanotide, revealing ligand-specific interactions and activation mechanisms.

bioRxiv · Apr 22, 2021Biochemistry

Quantifying the heterogeneity of macromolecular machines by mass photometry

A. Sonn Segev, K. Belacic, T. Bodrug, G. Young, R. T. VanderLinden, B. Schulman, J. Schimpf, T. Friedrich, P. Vinh Dip, T. Schwartz, B. Bauer, J.-M. Peters, W. B. Struwe, J. L. Benesch, N. G. Brown, , P. Kukura

This paper demonstrates that mass photometry accurately quantifies sample heterogeneity with high resolution and minimal volume, outperforming negative stain electron microscopy in detecting proteasome assemblies.

bioRxiv · Dec 4, 2019Biophysics