GTP signaling links metabolism, DNA repair, and responses to genotoxic stress
W. Zhou, Z. Zhao, A. Lin, J. Yang, J. Xu, K. Wilder-Romans, A. Yang, J. Li, S. Solanki, J. Speth, N. Walker, A. J. Scott, A. U. Kothari, Y. Yao, E. R. Peterson, , D. R. Wahl
This study identifies a GTP-mediated signaling pathway linking metabolism to DNA repair and resistance to genotoxic stress in glioblastoma and non-malignant cells.
bioRxiv · Apr 12, 2023Cancer Biology