Cancer BiologybioRxiv
Therapeutic role of recurrent ESR1-CCDC170 gene fusions in breast cancer endocrine resistance
L. Li, L. Lin, J. Veeraraghavan…·x. wang
This study investigates the role of ESR1-CCDC170 gene fusions in breast cancer endocrine resistance, showing they reduce endocrine sensitivity and can be targeted with HER2/SRC inhibitors.
DOI 10.1186/s13058-020-01325-3