Author

J. Zapata

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Research Focus:development & morphogenesis· 1 Research Focus:protein folding & dynamics· 1 Organism:yeast· 1

Frequent Co-Authors

A. Moeller· 1 shared D. Januliene· 1 shared D. Kellogg· 1 shared D. Waghray· 1 shared G. Hummer· 1 shared H. Chen· 1 shared H. Jung· 1 shared I. L. Urbatsch· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBiophysics

A. Moeller

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2 papers

Recent·Most cited

Tracing the substrate translocation mechanism in P-glycoprotein

T. Gewering, D. Waghray, K. Parey, H. Jung, N. N. B. Tran, J. Zapata, P. Zhao, H. Chen, D. Januliene, G. Hummer, I. L. Urbatsch, A. Moeller, Q. Zhang

This study reveals the substrate translocation mechanism in P-glycoprotein by determining cryoEM structures and using molecular dynamics simulations to identify conformational changes in TM1 that regulate transport.

bioRxiv · Apr 28, 2022 · PreprintBiophysics

A conserved Lkb1 signaling axis modulates TORC2 signaling in budding yeast

M. Alcaide Gavilan, R. Lucena, K. Schubert, K. Artiles, J. Zapata, D. Kellogg

The paper shows that Lkb1 homologs in budding yeast modulate TORC2 signaling through a pathway independent of Snf1/AMPK, linking carbon source availability to cell growth and size regulation.

bioRxiv · Apr 2, 2018Cell Biology