J.-B. Fiche

Integrin-like adhesin CglD confers traction and stabilizes bacterial focal adhesions involved in myxobacterial gliding motility

The paper identifies CglD as a β-integrin-like adhesin in Myxococcus xanthus that stabilizes bacterial focal adhesions and enables gliding motility through mechanosensory and mechanotransductory functions.

Multi-scale dynamic imaging reveals that cooperative motility behaviors promote efficient predation in bacteria

The paper uses multiscale imaging to show that cooperative motility behaviors in Myxococcus xanthus enhance predation efficiency by combining A- and S-motile cells.

Multiple parameters shape the 3D chromatin structure of single nuclei

This study shows that multiple factors influence the 3D chromatin structure of single nuclei during Drosophila embryonic development.

MiSiC, a general deep learning-based method for the high-throughput cell segmentation of complex bacterial communities

MiSiC is a deep learning method for segmenting bacterial cells in complex communities, enabling analysis of interspecies interactions with minimal parameter adjustment.

CglB adhesins secreted at bacterial focal adhesions mediate gliding motility

The paper identifies CglB as a substratum-coupling protein secreted by the gliding complex in Myxococcus xanthus, revealing a mechanism for force transduction and a novel secretion process.

A plasma membrane nanoplatform ensures signal specificity during osmotic signaling in plants

The paper shows that Rho GTPase nanodomains at the plasma membrane ensure signal specificity during osmotic signaling in plants by transducing reactive oxygen species production.

G1/S transcription factors assemble in discrete clusters that increase in number as cells grow

The paper uses PALM to show SBF/MBF transcription factors form clusters in yeast cells, with cluster number increasing as cells grow.

Microscopy-based chromosome conformation capture enables simultaneous visualization of genome organization and transcription in intact organisms

The paper introduces Hi-M, a microscopy-based method to simultaneously visualize genome organization and transcription in single nuclei of Drosophila embryos, revealing changes in 3D chromatin structure during transcriptional activation.

In vivo phosphatidylserine variations steer Rho GTPase signaling in a cell-context dependent manner

The paper shows phosphatidylserine regulates Rho GTPase signaling in Arabidopsis by modulating ROP6 nanoclusters and auxin signaling during root development.

Single-cell absolute contact probability detection reveals that chromosomes are organized by multiple, low-frequency yet specific interactions

The paper uses high-content super-resolution microscopy to show that TADs and compartments are organized by low-frequency, specific interactions regulated by epigenetics and transcription.