Author

K. Chapman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Pharmacology & Toxicology· 1 Physiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Liu· 1 shared A. Marson· 1 shared A. Mocciaro· 1 shared A. Schuldt· 1 shared A. Shah· 1 shared C. B. Buckley· 1 shared C. L. Nicholson· 1 shared C. Wyrwoll· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperPharmacology & Toxicology

A. Liu

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Author profile →

4 papers

Recent·Most cited

CEP peptide and cytokinin pathways converge on CEPD glutaredoxins to inhibit root growth

M. Taleski, K. Chapman, O. Novak, T. Schmulling, M. Frank, M. A. Djordjevic

This study shows that CEP and cytokinin pathways intersect by converging on CEPD glutaredoxins to inhibit root growth.

bioRxiv · Jul 5, 2022 · PreprintPlant Biology

GLUCOCORTICOIDS REGULATE MITOCHONDRIAL FATTY ACID OXIDATION IN FETAL CARDIOMYOCYTES

J. R. Ivy, R. N. Carter, J.-F. Zhao, C. B. Buckley, H. Urquijo, E. A. Rog-Zielinska, E. Panting, L. Hrabalkova, C. L. Nicholson, E. J. Agnew, M. W. Kemp, N. M. Morton, S. J. Stock, C. Wyrwoll, I. N. Ganley, K. Chapman

This study shows that endogenous glucocorticoids promote fatty acid oxidation in fetal cardiomyocytes through gene expression changes, while exogenous glucocorticoids may disrupt this process.

bioRxiv · Apr 30, 2021Physiology

Identification of SARS-CoV-2 induced pathways reveal drug repurposing strategies

N. Han, W. Hwang, K. Tzelepis, P. Schmerer, E. Yankova, M. MacMahon, W. Lei, N. M. Katritsis, A. Liu, A. Schuldt, R. Harris, K. Chapman, F. McCaughan, F. Weber, T. Kouzarides

The paper identifies 200 approved drugs that target SARS-CoV-2-induced pathways, with 40 in clinical trials, and classifies them into viral replication and immune response mechanisms.

bioRxiv · Aug 24, 2020Pharmacology & Toxicology

Light-Activated Cell Identification and Sorting (LACIS): A New Method to Identify and Select Edited Clones on a Microfluidic Device

A. Mocciaro, T. Roth, H. Bennett, M. Soumillon, A. Shah, J. Hiatt, K. Chapman, A. Marson, G. Lavieu

The paper introduces LACIS, a microfluidic method for identifying and sorting edited clones using Opto-Electronic Positioning, enabling rapid and efficient clonal selection after CRISPR-Cas9 editing.

bioRxiv · Oct 17, 2017Bioengineering