Author
K. H. Eng
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2019-2023 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author links6 papers
Recent·Most cited
- Cancer BiologybioRxivPreprintDOI 10.1101/2023.12.01.569685
- PathologybioRxivPreprint
Stromal resistance to castration-induced prostate regression in a mouse model of benign prostatic hyperplasia
R. Zhang, S. Singh, C. Pan…·K. L. Nastiuk
This study shows that stromal compartments in a mouse model of BPH are resistant to castration-induced regression, suggesting the need for additional therapies.
DOI 10.1101/2022.12.07.519520 - Cancer BiologybioRxivPreprint
Glucocorticoid signaling delays castration-induced regression in murine models of prostate cancer
A. Maolake, R. Zhang, K. Sha…·K. L. Nastiuk
This study shows that glucocorticoid signaling delays castration-induced regression in murine prostate cancer models by maintaining tumor proliferation through GR activation, which can be blocked by the GR antagonist relacorilant.
- ImmunologybioRxivPreprint
ARS2-directed alternative splicing mediates CD28 driven T cell glycolysis and effector function
G. A. Holling, A. P. Sharda, M. M. Honikel…·S. H. Olejniczak
This study shows ARS2 promotes CD28-driven T cell glycolysis and effector function through alternative splicing of Pkm2, enhancing anti-tumor immunity.
DOI 10.1101/2021.05.07.442963 - Cancer BiologybioRxivPreprint
Patient derived models of bladder cancer amplify tumor specific gene expression compared to surgical specimen while maintaining gene expression of molecular subtype and epithelial mesenchymal transition markers
M. Mastri, S. Ramakrishnan, S. Shah…·W. J. HUSS
This study compares gene expression profiles of patient-derived models (PDMs) with surgical specimens of bladder cancer, finding PDXs most similar to original tumors while maintaining EMT and molecular subtype markers.
DOI 10.1101/2021.02.10.430614 - Cancer BiologybioRxiv
Alternative polyadenylation drives oncogenic gene expression in pancreatic ductal adenocarcinoma
S. Venkat, A. A. Tisdale, J. R. Schwarz…·M. E. Feigin
This study identifies APA-driven gene expression changes in pancreatic ductal adenocarcinoma, revealing miRNA loss and therapeutic targets like CK1.
DOI 10.1101/gr.257550.119