Author

K. Hyrc

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Diwan· 2 shared A. Javaheri· 2 shared A. Kovacs· 2 shared D. R. Rawnsley· 2 shared K. B. Margulies· 2 shared X. Ma· 2 shared A. A. Desai· 1 shared A. Asnani· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

A. Diwan

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

TRAF2, an innate immune sensor, reciprocally regulates mitophagy and inflammation to maintain cardiac myocyte homeostasis.

X. Ma, D. R. Rawnsley, A. Kovacs, M. Islam, J. T. Murphy, C. Zhao, M. Kumari, L. M. Foroughi, H. Liu, K. Hyrc, S. Evans, B. A. French, K. B. Margulies, A. Javaheri, B. Razani, , A. Diwan

This study shows TRAF2 regulates mitophagy and inflammation in cardiac myocytes to prevent cell death and maintain homeostasis.

bioRxiv · Jun 12, 2021Cell Biology

Apolipoprotein M attenuates anthracycline cardiotoxicity and lysosomal injury

Z. Guo, C. Valenzuela Ripoll, A. Picataggi, D. R. Rawnsley, M. Ozcan, J. A. Chirinos, E. Chendamarai, A. Girardi, T. Riehl, H. Evie, A. Diab, A. Kovacs, K. Hyrc, X. Ma, A. Asnani, , A. Javaheri

This paper investigates the role of apolipoprotein M in anthracycline cardiotoxicity, finding that ApoM protects against cardiac dysfunction and lysosomal injury through the autophagy-lysosome pathway.

bioRxiv · Jan 12, 2021Pharmacology & Toxicology