Author

K. Littlefield

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Pekosz· 3 shared J. L. Mankowski· 2 shared R. Zhou· 2 shared S. Dhakal· 2 shared S. L. Klein· 2 shared A. A. Tobian· 1 shared A. Braxton· 1 shared A. Casadevall· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersImmunology

A. Pekosz

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ImmunologybioRxivFeb 14, 2022

SARS-CoV-2-specific T cells associate with reduced lung function and inflammation in pulmonary post-acute sequalae of SARS-CoV-2

K. Littlefield, R. Watson, J. Schneider…·B. Palmer

This study finds that elevated SARS-CoV-2-specific T cells in individuals with pulmonary PASC correlate with increased inflammation and reduced lung function.

DOI 10.1371/journal.ppat.1010359

humanproteomics

𝕏 PostBluesky

ImmunologybioRxivJun 28, 2021

A bacterial extracellular vesicle-based intranasal vaccine against SARS-CoV-2 protects against disease and elicits neutralizing antibodies to wild-type virus and Delta variant

L. Jiang, T. Driedonks, M. Lowman…·K. W. Witwer

DOI 10.1002/jev2.12192

mouseexperimental assay

𝕏 PostBluesky

MicrobiologybioRxivApr 2, 2021

Sex differences in lung imaging and SARS-CoV-2 antibody responses in a COVID-19 golden Syrian hamster model

S. Dhakal, C. A. Ruiz-Bedoya, R. Zhou…·S. L. Klein

This study shows that male golden Syrian hamsters experience more severe lung disease and lower antiviral antibody responses compared to females after SARS-CoV-2 infection.

DOI 10.1128/mbio.00974-21

mouseimaging

𝕏 PostBluesky

ImmunologybioRxivPreprintOct 8, 2020

CD8+ T cell responses in convalescent COVID-19 individuals target epitopes from the entireSARS-CoV-2 proteome and show kinetics of early differentiation

H. Kared, A. D. Redd, E. M. Bloch…·T. C. Quinn

The paper identifies CD8+ T cell epitopes across the SARS-CoV-2 proteome in convalescent individuals and shows their differentiation kinetics and correlation with immune markers.

DOI 10.1101/2020.10.08.330688

humanflow cytometry

𝕏 PostBluesky