Deep mutational scanning reveals sequence to function constraints for SWEET family transporters
K. Narayanan, A. T. Weigle, L. Xu, X. Mi, C. Zhang, L.-Q. Chen, E. Procko, D. Shukla
This study uses deep mutational scanning to analyze sequence-function relationships in the plant SWEET transporter AtSWEET13, identifying mutations that enhance transport function and revealing constraints in transmembrane helix 4.
bioRxiv · Jun 28, 2024 · PreprintPlant Biology