Author

K. Nosol

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. A. Kossiakoff· 2 shared A. D. Finzi· 1 shared A. Rein· 1 shared D. Glebe· 1 shared D. Zakrzewicz· 1 shared E. A. Tatham· 1 shared H. Liu· 1 shared J. Geyer· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

A. A. Kossiakoff

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2 papers

Recent·Most cited

Structure of hepatitis B/D antiviral drug Bulevirtide bound to its receptor protein NTCP

H. Liu, D. Zakrzewicz, K. Nosol, R. N. Irobalieva, S. Mukherjee, R. Bang-Soerensen, N. Goldmann, S. Kunz, L. Rossi, A. A. Kossiakoff, S. Urban, D. Glebe, J. Geyer, K. P. Locher

The paper determines the cryo-EM structure of bulevirtide bound to NTCP, revealing its mechanism of inhibiting HBV/HDV entry and providing insights for drug development.

bioRxiv · Jan 22, 2024 · PreprintBiochemistry

CryoEM Structures of the Human HIV-1 Restriction Factor SERINC3 and Function as a Lipid Transporter

S. A. Leonhardt, M. D. Purdy, J. R. Grover, Z. Yang, S. Poulos, W. E. McIntire, E. A. Tatham, S. Erramilli, K. Nosol, K. K. Lai, S. Ding, M. Lu, P. D. Uchil, A. D. Finzi, A. Rein, , M. Yeager

The paper shows SERINC3 has a structure similar to lipid transporters and demonstrates its lipid flipping activity, which correlates with reduced HIV-1 infectivity.

bioRxiv · Jul 6, 2022 · PreprintBiophysics