Author

K. Voutetakis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Pandit· 3 shared e. chevet· 3 shared J. Samal· 3 shared R. Pineau· 3 shared T. Avril· 3 shared A. Chatziioannou· 2 shared A. Obiedat· 2 shared A. Samali· 2 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

A. Pandit

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Local intracerebral Inhibition of IRE1 by MKC8866 sensitizes glioblastoma to irradiation/chemotherapy in vivo.

P.-J. Le Reste, R. Pineau, K. Voutetakis, J. Samal, G. Jegou, S. Lhomond, A. M. Gorman, A. Samali, J. B. Patterson, Q. Zeng, A. Pandit, M. AUBRY, N. Soriano, A. Etcheverry, J. Mosser, , e. chevet

The paper develops a novel immunocompetent GBM model to test the effect of IRE1 inhibition on treatment efficacy in vivo.

bioRxiv · Feb 20, 2020Cancer Biology

Novel IRE1-dependent proinflammatory signaling controls tumor infiltration by myeloid cells.

J. Obacz, J. Archambeau, P. J. Le Reste, R. Pineau, K. Barroso, E. Vlachavas, K. Voutetakis, T. Fainsod-Levi, A. Obiedat, Z. Granot, B. Tirosh, J. Samal, A. Pandit, J. Patterson, Q. Zheng, , e. chevet

This study identifies an IRE1-dependent proinflammatory signaling pathway in glioblastoma that promotes tumor invasion, angiogenesis, and myeloid cell infiltration.

bioRxiv · Jan 11, 2020Cancer Biology

Constitutive UPRER activation sustains tumor cell differentiation

D. Doultsinos, M. McMahon, K. Voutetakis, J. Obacz, R. Pineau, P.-J. Le Reste, A. Obiedat, J. Samal, J. B. Patterson, Q. Zheng, A. Samali, A. Pandit, B. Tirosh, A. Chatziioannou, E. Chevet, T. Avril

The paper shows that constitutive IRE1 activation maintains differentiation in glioblastoma cells by repressing stemness factors.

bioRxiv · Oct 22, 2019 · PreprintCancer Biology