L. A. Cavacini

The paper identifies unique borreliacidal epitopes on OspA using VHHs and evaluates their reactivity across OspA serotypes.

This paper determines the crystal structure of a protective B cell epitope on OspC, revealing its quaternary nature and informing vaccine design for Lyme disease.

This study shows that oral administration of a single nanobody provides broad protection against multiple ETEC strains by targeting conserved epitopes.

This study identifies an IgA monoclonal antibody that blocks SARS-CoV-2 Spike-ACE2 interaction and provides mucosal immunity.

This study evaluates the efficacy of secretory IgA2 and dimeric IgA2 antibodies against ETEC in a non-human primate model, finding that oral SIgA2 significantly reduced diarrheal attack rates.