Author

L. Ho

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

R. SOBOTA· 2 shared B. Kerouantan· 1 shared B. Reversade· 1 shared C. BONNARD· 1 shared C. D. Rodriguez· 1 shared C. Finelli· 1 shared C. K. LIM· 1 shared C. L. Wee· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersImmunology

R. SOBOTA

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Author profile →

3 papers

Recent·Most cited

Hippo Signaling Modulates Mechano-inflammatory Responses of Chondrocytes

X. Cai, C. Warburton, O. F. Perez, Y. Wang, L. Ho, C. Finelli, C. Wu, C. D. Rodriguez, L. Kaplan, T. M. Best, C.-Y. Huang, Z. Meng

This study shows that Hippo signaling modulates chondrocyte responses to mechanical overload by regulating NF-kappaB-mediated inflammation and matrix degradation.

bioRxiv · Jun 9, 2023 · PreprintCell Biology

Human NLRP1 is activated by ZAKa-driven ribotoxic stress response

K. S. ROBINSON, G. A. TOH, P. ROZARIO, S. BAYAT, Z. SUN, S. BAUERNFRIED, R. NADKARNI, C. R. HARAPAS, C. K. LIM, W. CHU, K. Y. TAN, C. BONNARD, R. SOBOTA, J. E. CONNOLLY, S. L. MASTERS, , F. L. Zhong

This paper identifies ZAKa-driven ribotoxic stress as a mechanism for activating human NLRP1, leading to pyroptosis in response to UVB and microbial ribotoxins.

bioRxiv · Jan 24, 2022 · PreprintImmunology

BRAWNIN: A sORF-encoded Peptide Essential for Vertebrate Mitochondrial Complex III Assembly

S. Zhang, C. Liang, C. Mary, B. Kerouantan, J. Francisco, N. S. Jagannathan, V. Olexiouk, J. H. Peh, C. Tang, G. Fidelito, S. Nama, R.-K. Cheng, C. L. Wee, L. C. Wang, P. D. Roggli, , L. Ho

The paper identifies BRAWNIN, a sORF-encoded peptide critical for vertebrate mitochondrial complex III assembly, showing its role in oxidative phosphorylation and metabolic function.

bioRxiv · Jan 31, 2020 · PreprintCell Biology