C. Jeffries

TCGADEPMAP -- Mapping Translational Dependencies and Synthetic Lethalities within The Cancer Genome Atlas

TCGADEPMAP maps translational tumor dependencies and synthetic lethality using TCGA data, identifying novel targets like PAPSS1/2 with clinical implications.

Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2

This study isolates and characterizes synthetic nanobodies that neutralize SARS-CoV-2, identifying Sb23 with high affinity and neutralization activity.

Structure-based identification and functional characterization of an essential lipocalin in the malaria parasite Plasmodium falciparum

This study identifies and characterizes PfLCN, a lipocalin in Plasmodium falciparum, showing its role in oxidative stress response and parasite survival.

Structure of herpes simplex virus pUL7:pUL51, a conserved complex required for efficient herpesvirus assembly

This paper solves the structure of the HSV-1 pUL7:pUL51 complex, showing its conservation across herpesviruses and its potential role in membrane remodeling during virus assembly.

A systematic review and meta-analysis of the human blood index of the major African malaria vectors

This study systematically reviews and meta-analyzes the human blood index (HBI) of major African malaria vectors, finding higher HBI in Anopheles gambiae and An. funestus compared to An. arabiensis, with location being a stronger predictor than species.

Assessing the blood-host plasticity and dispersal rate of the malaria vector Anopheles coluzzii

The paper introduces a method to assess blood-host plasticity and dispersal rate of Anopheles coluzzii using blood-meal source detection and molecular analysis.