L. Katsimpardi

The paper shows that inflammation causes age-related loss of tissue-resident macrophages, which cannot be replaced by hematopoietic stem cell-derived cells, and that reducing inflammation prevents this loss and improves liver aging.

This study shows that motor neurons enhance muscle stem cell function by boosting protein synthesis and mitochondrial activity, which is critical for muscle regeneration and is disrupted in diseases like muscular dystrophy and aging.