Author

J. McPartlan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

A. Apffel· 1 shared A. D'Andrea· 1 shared A. Gonzalez· 1 shared A. J. Bass· 1 shared A. Soerens· 1 shared A. Tserniak· 1 shared B. Gaeta· 1 shared C. Mandl· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Apffel

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Route of self-amplifying mRNA vaccination modulates the establishment of pulmonary resident memory CD8 and CD4 T cells

M. Kunzli, S. O'Flanagan, M. LaRue, P. Talukder, T. Dileepan, A. Soerens, C. Quarnstrom, S. Wijeyesinghe, Y. Ye, J. McPartlan, J. Mitchell, C. Mandl, R. Vile, M. Jenkins, R. Ahmed, , D. Masopust

This study investigates how different routes of self-amplifying mRNA vaccination affect the establishment of pulmonary resident memory T cells in mice.

bioRxiv · Jun 2, 2022Immunology

WRN Helicase is a Synthetic Lethal Target in Microsatellite Unstable Cancers

E. Chan, T. Shibue, J. McFarland, B. Gaeta, J. McPartlan, M. Ghandi, J. B. Liu, J.-B. Lazaro, N. Dumont, A. Gonzalez, A. Apffel, S. O. Ali, L. Leung, E. Roberts, E. Rizvochenko, , A. J. Bass

The paper identifies WRN helicase as a synthetic lethal target in microsatellite unstable cancers through CRISPR/Cas9 and RNAi screens, showing its essentiality in MSI cell lines.

bioRxiv · Dec 21, 2018Cancer Biology