K. Schmidt

Development of an Experimental Protocol to Study the Neural Control of Force and Impedance in Wrist Movements with Robotics and fMRI

This study develops an experimental protocol to decouple force and impedance control in wrist movements using robotics and fMRI, showing distinct torque and stiffness responses to different force conditions.

SGLT2 inhibitors attenuate endothelial to mesenchymal transition and cardiac fibroblast activation

This study shows SGLT2 inhibitors reduce endothelial to mesenchymal transition and cardiac fibroblast activation through effects on mitochondrial respiration, actin cytoskeleton, and specific transporters.

The structure of NAD+ consuming protein Acinetobacter baumannii TIR domain shows unique kinetics and conformations.

The paper reports the crystal structure of Acinetobacter baumannii TIR domain and its NAD+ hydrolase activity, showing conformational changes and kinetic effects upon substrate binding.

Relationship of maternal cytomegalovirus-specific antibody responses and viral load to vertical transmission risk following primary maternal infection in a rhesus macaque model

This study investigates maternal cytomegalovirus (CMV) antibody responses and viral load in rhesus macaques to determine their association with vertical transmission risk, finding no link between plasma viremia or humoral responses and congenital CMV in immunocompetent dams.

Dancing the Nanopore limbo - Nanopore metagenomics from small DNA quantities for bacterial genome reconstruction

This study evaluates using lower DNA quantities for Nanopore sequencing in metagenomics, showing that high-quality MAGs can be recovered from as little as 35 ng of input DNA.

How benthic sediment microbial communities respond to glyphosate and its metabolite: A microcosm experiment

This study examines how benthic sediment microbial communities respond to glyphosate and its metabolite through a microcosm experiment, finding no significant changes in community composition.

Concurrent Contribution of Co-contraction to Error Reduction during Dynamic Adaptation of the Wrist

The paper validates MR-SoftWrist measurements of wrist adaptation and shows that impedance control via co-contraction reduces trajectory errors beyond adaptation.

Bacillus subtilis remains translationally active after CRISPRi-mediated replication initiation arrest

This study shows that Bacillus subtilis remains translationally active after CRISPRi-mediated replication initiation arrest, without DNA damage response or growth cessation.

B cells are addicted to immunoglobulin production in the ER

The paper shows that B cells rely on ER-resident immunoglobulin heavy chains for ER homeostasis and mitochondrial function, independent of BCR signaling.

Integration host factor regulates colonization factors in the bee gut symbiont Frischella perrara

This study identifies IHF as a regulator of colonization factors in the bee gut symbiont F. perrara, showing its role in metabolite production and gut colonization.

Optimization of anastomotic technique and gastric conduit perfusion with hyperspectral imaging in an experimental model for minimally invasive esophagectomy

This study uses hyperspectral imaging to evaluate anastomotic technique and gastric conduit perfusion in a porcine model of minimally invasive esophagectomy, finding that short staplers and caudal anastomotic positions maintain tissue oxygenation.

Characterization of the microbiota associated with 12-week-old bovine fetuses exposed to divergent in utero nutrition

This study characterizes the microbiota in 12-week-old bovine fetuses and finds that maternal nutrition influences early fetal microbial communities.

The nasopharyngeal, ruminal, and vaginal microbiota and the core taxa shared across these microbiomes in virgin yearling heifers exposed to divergent in utero nutrition during their first trimester of gestation and in pregnant beef heifers in response to mineral supplementation

This study examines the microbiota of nasopharyngeal, ruminal, and vaginal samples in beef heifers exposed to different in utero nutrition and mineral supplementation, finding little impact on microbiome diversity and identifying shared microbial taxa across body sites.

Metagenome-assembled genomes of phytoplankton communities across the Arctic Circle

This study assembles metagenome-assembled genomes (MAGs) from Arctic and non-polar phytoplankton communities to compare their genetic diversity and functional differences.

An endocrine-hepato-muscular metabolic cycle links skeletal muscle atrophy and hyperglycemia in type 2 diabetes

This study identifies an endocrine-hepato-muscular metabolic cycle linking hyperglycemia and skeletal muscle atrophy in type 2 diabetes through dysregulated alanine metabolism and ALT enzyme activity.

A Cytoskeletal Protein Complex is Essential for Division of Intracellular Amastigotes of Leishmania mexicana

This study identifies KHAP1 and KHAP2 as KHARON partners, showing that the subpellicular complex is essential for cytokinesis but not flagellar trafficking in Leishmania mexicana.

Strong positive biodiversity-productivity relationships in a subtropical forest experiment

The paper demonstrates a strong positive biodiversity-productivity relationship in a subtropical forest experiment, showing increased productivity with species richness and complementary effects over time.