Author

L. Rosas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. L. Mora· 3 shared M. Rojas· 3 shared T. Khaliullin· 2 shared A. B. Hummon· 1 shared A. Green· 1 shared A. R. Bhagwani· 1 shared B. Piper· 1 shared D. Farkas· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBiochemistry

A. L. Mora

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Single Cell MALDI-MSI Analysis of Lipids and Proteins within a Replicative Senescence Fibroblast Model

E. R. Sekera, L. Rosas, J. H. Holbrook, Q. D. Angeles-Lopez, T. Khaliullin, M. Rojas, A. L. Mora, A. B. Hummon

This study uses MALDI-MSI to analyze lipids and proteins in human lung fibroblasts, revealing senescence-related changes at the single-cell level.

bioRxiv · Mar 13, 2024Biochemistry

RAB7 deficiency impairs pulmonary artery endothelial function and promotes pulmonary hypertension

B. Piper, S. Bogamuwa, T. Hossain, D. Farkas, L. Rosas, A. Green, G. Newcomb, N. Sun, J. C. Horowitz, A. R. Bhagwani, H. Yang, T. V. Kudryashova, M. Rojas, A. L. Mora, P. Yan, , L. Farkas

This study shows RAB7 deficiency impairs endothelial function and causes pulmonary hypertension in mice, with potential for RAB7 activation as a therapeutic strategy.

Journal of Clinical Investigation · Feb 1, 2024Peer-reviewedPhysiology

Optimal transport for mapping senescent cells in spatial transcriptomics

N. D. Nguyen, L. Rosas, T. Khaliullin, P. Jiang, E. Hasanaj, J. A. Ovando, M. Bueno, M. Konigshoff, O. Eickelberg, M. Rojas, A. L. Mora, J. Lugo-Martinez, Z. Bar-Joseph

The paper develops scDOT, a method combining spatial transcriptomics and single-cell RNA-seq with optimal transport to improve spatial mapping of senescent cells and identify novel genes involved in cell-cell interactions.

bioRxiv · Aug 16, 2023Cell Biology