Author

L. Shehata

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

M. Pepper· 2 shared A. C. Walls· 1 shared A. Palser· 1 shared A. Schaefer· 1 shared B. Brown· 1 shared B. D. Hondowicz· 1 shared B. Fiala· 1 shared B. Gern· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

M. Pepper

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3 papers

Recent·Most cited

IL-4 downregulates BCL6 to promote memory B cell selection in germinal centers

L. Shehata, C. D. Thouvenel, B. D. Hondowicz, L. A. Pew, D. J. Rawlings, J. Choi, M. Pepper

This study shows IL-4 downregulates BCL6 in GC B cells to promote memory B cell selection and regulate affinity maturation.

bioRxiv · Jan 26, 2023 · PreprintImmunology

Elicitation of potent neutralizing antibody responses by designed protein nanoparticle vaccines for SARS-CoV-2

A. C. Walls, B. Fiala, A. Schaefer, S. Wrenn, M. N. Pham, M. Murphy, L. V. Tse, L. Shehata, M. A. O'Connor, C. Chen, M. J. Navarro, M. C. Miranda, D. Pettie, R. Ravichandran, J. C. Kraft, , N. P. King

This study designs SARS-CoV-2 nanoparticle vaccines that induce strong neutralizing antibodies in mice, with higher titers and lower doses than existing trimer vaccines.

bioRxiv · Aug 11, 2020Immunology

TGFβ restricts T cell function and bacterial control within the tuberculous granuloma

B. Gern, K. N. Adams, C. R. Plumlee, C. R. Stoltzfus, L. Shehata, K. Busman-Sahay, S. G. Hansen, M. K. Axthelm, L. J. Picker, J. D. Estes, K. B. Urdahl, M. Y. Gerner

This study shows that TGFβ suppresses T cell function and bacterial control in tuberculous granulomas by inhibiting IFNγ production in T helper 1 cells.

bioRxiv · Jul 9, 2019Immunology