K. B. Urdahl

This study evaluates BCG vaccine efficacy using an ultra-low dose Mtb murine model, showing enhanced protection compared to conventional models.

This study shows that the live attenuated Mtb vaccine candidate ΔLprG provides better protection than BCG in a low dose murine challenge model, reducing detectable infection and containing it anatomically.

This study shows that prior exposure to mycobacteria remodels alveolar macrophages, enhancing their pro-inflammatory response to Mtb infection through both intrinsic changes and environmental factors.

This study shows TOLLIP prevents lipid-induced EIF2 activation in alveolar macrophages, which allows Mycobacterium tuberculosis replication and reduces protection.

CytoMAP is a spatial analysis toolbox that identifies cellular networks and tissue organization features in lymphoid tissues using 2D/3D imaging data.

This study shows that TGFβ suppresses T cell function and bacterial control in tuberculous granulomas by inhibiting IFNγ production in T helper 1 cells.

This study shows BCG vaccination shifts infected cell types in mice, with T cell activation preceding bacterial burden reduction.